Results 61 to 70 of about 103,699 (311)

Parallel Operation of Self‐Limited Analog Programming for Fast Array‐Level Weight Programming and Update

open access: yesAdvanced Intelligent Systems, 2020
Memristive neural networks perform vector matrix multiplication efficiently, which is used for the accelerator of neuromorphic computing. To train the memristor cells in a memristive neural network, the analog conductance state of the memristor should be
Hanchan Song   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An implementation of a plasma physics application for distributed-memory supercomputers using a directive-based programming framework

open access: yesRevista Colombiana de Computación
To extract performance from supercomputers, programmers in the High Performance Computing (HPC) community are often required to use a combination of frameworks to take advantage of the multiple levels of parallelism. However, over the years, efforts have
Christian Asch   +2 more
doaj   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

State-of-the-Art in Parallel Computing with R [PDF]

open access: yes, 2009
R is a mature open-source programming language for statistical computing and graphics. Many areas of statistical research are experiencing rapid growth in the size of data sets. Methodological advances drive increased use of simulations.
Hao Yu   +11 more
core   +1 more source

Quantum Computer Architecture Toward Full-Stack Quantum Accelerators

open access: yesIEEE Transactions on Quantum Engineering, 2020
This article presents the definition and implementation of a quantum computer architecture to enable creating a new computational device—a quantum computer as an accelerator.
Koen Bertels   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Scheduling parallel data retrievals for non-consecutive broadcast in MIMO wireless networks

open access: yes, 2012
Wireless data broadcast is usually used to disseminate the public information to considerable clients in wireless environment. Based on the development of mobile device, some mobile devices can simultaneously use multiple antennae to process some ...
Hong Shen   +5 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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