Results 81 to 90 of about 103,699 (311)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

IBM AIX Parallel Environment Parallel Programming

, 2007
Introduction to SETL. Springer-Verlag, New York, 1986. [24] Seevers, B., Quinn, M. and Hatcher, P. A Parallel Programming Environment Supporting Multiple Data-Parallel Modules.
Programming The, Paralation Model, G. The, Reference Edition, Van Rosendale, Architecture-independent Parallel   +5 more
core  

G-SAIP: Graphical Sequence Alignment Through Parallel Programming in the Post-Genomic Era. [PDF]

Evol Bioinform Online, 2023
Piña JS, Orozco-Arias S, Tobón-Orozco N, Camargo-Forero L, Tabares-Soto R, Guyot R.   +5 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Variable grain architectures for MPP computation and structured parallel programming

, 1997
The paper discusses the relationships between hierarchically composite MPP architectures and the software technology derived from the structured parallel programming methodology, in particular the architectural support to successive modular refinements ...
VANNESCHI, MARCO
core  

Using OpenMP: Portable Shared Memory Parallel Programming

Journal of Computer Science and Technology, 2010
The book Using OpenMP: Portable Shared Memory Parallel Programming, presents OpenMP more than appropriately, from the perspective of high performance computing, which traditionally has provided most (if not all) the parallel software development ...
Fernando Gustavo Tinetti
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Structured Parallel Programming: patterns for efficient computation.

Journal of Computer Science and Technology, 2015
In this book the authors, who are parallel computing experts and industry insiders, describe how to design and implement maintainable and efficient parallel algorithms using a pattern-based approach.
Armando Eduardo De Giusti
doaj