Results 41 to 50 of about 22,218 (212)

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI): Conference Report

Biomimetics, 2019
The International Work Conference on Bioinspired Intelligence (IWOBI) is an annual event that comprises both an international peer-reviewed scientific conference and a set of workshops and other activities in order to foster the research abilities and ...
Juan Luis Crespo-Mariño
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

High-Performance Computing Training by Skills for Advanced Computing Ecosystems

Revista UIS Ingenierías
High-Performance Computing (HPC) is one of the pillars of developing modern science and disruptive technologies, uniting computer architectures and parallel programming into multidisciplinary interactions to face domain-specific problems.
Carlos Jaime Barrios-Hernandez , Robinson Rivas, Xavier Besseron, Gilberto Diaz, Yiannis Georgiou, Pedro Velho   +5 more
doaj   +1 more source

Algorithms for determining the circumstances relevant for the case in the software for informational-technological support of judicial decisions

Russian Journal of Economics and Law, 2019
Objective: to create a computer program of information technology support for making motivated court decisions; to obtain constructive criticism of the grounds of and objections to claim presented in the software forms in order to improve it.
S. B. Polyakov, I. A. Gilev
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A lightweight, flow-based toolkit for parallel and distributed bioinformatics pipelines

BMC Bioinformatics, 2011
Background Bioinformatic analyses typically proceed as chains of data-processing tasks. A pipeline, or 'workflow', is a well-defined protocol, with a specific structure defined by the topology of data-flow interdependencies, and a particular ...
Cieślik Marcin, Mura Cameron
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Visual programming language environment for different IoT and robotics platforms in computer science education

CAAI Transactions on Intelligence Technology, 2018
This study presents the authors’ recent research and application of a new visual programming language and its development environment: VIPLE (Visual IoT/Robotics Programming Language Environment) at Arizona State University (ASU).
Gennaro De Luca, Zhongtao Li, Sami Mian, Yinong Chen   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source