Results 41 to 50 of about 138,723 (254)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A Review of Parallel Robots: Rehabilitation, Assistance, and Humanoid Applications for Neck, Shoulder, Wrist, Hip, and Ankle Joints

Robotics, 2023
This review article presents an in-depth examination of research and development in the fields of rehabilitation, assistive technologies, and humanoid robots.
Victoria E. Abarca, Dante A. Elias
doaj   +1 more source

Kinematics and workspace analysis of a 3ppps parallel robot with u-shaped base [PDF]

, 2017
This paper presents the kinematic analysis of the 3-PPPS parallel robot with an equilateral mobile platform and a U-shape base. The proposed design and appropriate selection of parameters allow to formulate simpler direct and inverse kinematics for the ...
Baron, Luc, Chablat, Damien, Jha, Ranjan
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Robustness multi-objective optimization for parallel robot based on subregional meta-heuristic iteration [PDF]

Journal of Intelligent Manufacturing and Special Equipment
Purpose – This work aims to provide a rapid robust optimization design solution for parallel robots or mechanisms, thereby circumventing inefficiencies and wastage caused by empirical design, as well as numerous physical verifications, which can be ...
Mingzhe Tao, Jinghua Xu, Shuyou Zhang, Jianrong Tan   +3 more
doaj   +1 more source

Development of Robot-Assisted Untact Swab Sampling System for Upper Respiratory Disease

Applied Sciences, 2020
We propose a new telerobotic system for untact swab sampling to prevent the infection of medical staff during upper respiratory sample collection. The system consists of a slave robot and two master devices.
Joonho Seo, Seongbo Shim, Haejune Park, Junmin Baek, Jang Ho Cho, Nam-Hee Kim   +5 more
doaj   +1 more source

Workspace and Singularity analysis of a Delta like family robot [PDF]

, 2015
Workspace and joint space analysis are essential steps in describing the task and designing the control loop of the robot, respectively. This paper presents the descriptive analysis of a family of delta-like parallel robots by using algebraic tools to ...
A Pashkevich, A Soni, C Gosselin, D Chablat, D Lazard, DA Cox, Damien Chablat, E Ottaviano, G Castelli, IA Bonev, IA Bonev, J Hansen, JA Snyman, M Zein, M. Hebsacker, O. Bohigas   +15 more
core   +4 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Passive Exercise Adaptation for Ankle Rehabilitation Based on Learning Control Framework

Sensors, 2020
Ankle injuries are among the most common injuries in sport and daily life. However, for their recovery, it is important for patients to perform rehabilitation exercises.
Fares J. Abu-Dakka, Angel Valera, Juan A. Escalera, Mohamed Abderrahim, Alvaro Page, Vicente Mata   +5 more
doaj   +1 more source

A hyper-redundant manipulator [PDF]

, 1994
“Hyper-redundant” manipulators have a very large number of actuatable degrees of freedom. The benefits of hyper-redundant robots include the ability to avoid obstacles, increased robustness with respect to mechanical failure, and the ability to perform ...
Burdick, Joel W., Chirikjian, Gregory S.
core   +1 more source