Results 41 to 50 of about 3,762 (237)
Paroxysmal limb weakness for ten years
DOI: 10.3969/j.issn.1672-6731.2017.07 ...
Meng-yu ZHANG +5 more
doaj
Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations [PDF]
Primary hypokalemic periodic paralysis (HOKPP) is an autosomal dominant disorder manifesting as recurrent periodic flaccid paralysis and concomitant hypokalemia. HOKPP is divided into type 1 and type 2 based on the causative gene.
Bendahhou +19 more
core +2 more sources
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu +14 more
wiley +1 more source
Muscle and brain sodium channelopathies: genetic causes, clinical phenotypes, and management approaches [PDF]
Voltage-gated sodium channels are essential for excitability of skeletal muscle fibres and neurons. An increasing number of disabling or fatal paediatric neurological disorders linked to mutations of voltage-gated sodium channel genes are recognised ...
Balestrini, S +3 more
core
An atypical phenotype of hypokalemic periodic paralysis caused by a mutation in the sodium channel gene SCN4A [PDF]
Familial hypokalemic periodic paralysis is an autosomal-dominant channelopathy characterized by episodic muscle weakness with hypokalemia. The respiratory and cardiac muscles typically remain unaffected, but we report an atypical case of a family with ...
Bendahhou +14 more
core +2 more sources
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Andersen-Tawil syndrome (ATS) is a rare condition consisting of ventricular arrhythmias, periodic paralysis, and dysmorphic features. In 2001, mutations in KCNJ2, which encodes the α subunit of the potassium channel Kir2.1, were identified in patients ...
Fish, Frank A +2 more
core +2 more sources
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng +8 more
wiley +1 more source
Personal HealthCare of Things: A novel paradigm and futuristic approach
Abstract This study provides an investigative approach and offers a complete review of research on Internet of Medical Things (IoMT), describing the progress in general and highlighting the research issues, trends, and future aspects of IoMT. Exploring a research strategy for IoMT systems is vital as the need for IoT in healthcare grows. By aggregating
Surbhi Gupta +5 more
wiley +1 more source
Hybrid Co3O4@Co3(HITP)2‐based chemiresitor was constructed for hydrogen sulfide detection at low‐temperature, which presented excellent sensing performance at room and refrigerant temperature. A proof of concept was conducted by monitoring hydrogen sulfide released from pork spoilage at both temperature using a portable device with a smartphone ...
Yongjiao Sun +9 more
wiley +1 more source

