Results 31 to 40 of about 492,436 (341)

The Physiology of Neurogenic Obesity: Lessons from Spinal Cord Injury Research

Obesity Facts, 2023
Background: A spinal cord injury (SCI) from trauma or disease impairs sensorimotor pathways in somatic and autonomic divisions of the nervous system, affecting multiple body systems.
David W McMillan, Gregory E. Bigford, Gary J. Farkas   +2 more
doaj   +1 more source

Antiviral treatment for Bell's palsy (idiopathic facial paralysis) [PDF]

, 2009
BACKGROUND: Antiviral agents against herpes simplex virus are widely used in the treatment of idiopathic facial paralysis (Bell's palsy), but their effectiveness is uncertain. Significant morbidity can be associated with severe cases.
Abiko, Adour, Adour KK Swanson, Ahangar, Allen, Allen, Antunes, Aquino, Axelsson, Bateman, Brandenberg, Chen, Diego, Egger, Engström, Goudakos, Hato, Hato, Hernández, House, Hultcranzt, Ibarrondo, Inanli, Katusic, Kawaguchi, May, McCormick, Morgan, Morgenlander, Murakami, Petruzelli, Pietersen, Pietersen, Ramos Macias, Ross, Rowlands, Roy, Salinas, Sipe, Stjernquist-Desatnik, Sugita, Sullivan, Takasu, Theil, Wolf, Yanagihara, Yeo, Zhou   +47 more
core   +3 more sources

Hydrocolloid‐Based Multiwavelength Stretchable QD‐OLED Patch for Simultaneous Neonatal Jaundice and Dermatitis Treatment with Biosignal Monitoring

Advanced Healthcare Materials, EarlyView.
Comparison of therapeutic and diagnostic applications of a surface‐emitting light source with multiwavelength emission characteristics. Abstract Conventional light‐emitting‐diode‐based light sources suffer from rigidity, localized heating, and poor adaptability to skin deformation, limiting their use in skin‐attached medical devices.
In Ho Kim, Young Woo Kim, Jae‐Young Jeong, Ye Ji Shin, Chaeyeong Lee, Jae Gyun Choi, Oh Kwan Kwon, Kyoung Hwa Kim, Sang Jik Kwon, Eou‐Sik Cho, Yongmin Jeon   +10 more
wiley   +1 more source

Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis. [PDF]

, 2019
Periodic paralysis is an ion channelopathy of skeletal muscle in which recurrent episodes of weakness or paralysis are caused by sustained depolarization of the resting potential and thus reduction of fiber excitability.
Cannon, Stephen C, DiFranco, Marino, Mi, Wentao, Quinonez, Marbella, Wu, Fenfen   +4 more
core   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Sex Dependent Disparities in the Central Innate Immune Response after Moderate Spinal Cord Contusion in Rat

Cells
Subacute spinal cord injury (SCI) displays a complex pathophysiology associated with pro-inflammation and ensuing tissue damage. Microglia, the resident innate immune cells of the CNS, in concert with infiltrating macrophages, are the primary ...
Mousumi Ghosh, Jinyoung Lee, Ashley N. Burke, Thomas A. Strong, Jacqueline Sagen, Damien D. Pearse   +5 more
doaj   +1 more source

Survival, Integration, and Axon Growth Support of Glia Transplanted into the Chronically Contused Spinal Cord

Cell Transplantation, 2005
Due to an ever-growing population of individuals with chronic spinal cord injury, there is a need for experimental models to translate efficacious regenerative and reparative acute therapies to chronic injury application.
D. J. Barakat, S. M. Gaglani, S. R. Neravetla, A. R. Sanchez, C. M. Andrade, Y. Pressman, R. Puzis, M. S. Garg, M. B. Bunge, Damien Daniel Pearse   +9 more
doaj   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Molecular pathology of acute spinal cord injury in middle-aged mice

Journal of Neuroinflammation
The median age at which spinal cord injuries occur has steadily increased from 29 to 43 over the last several decades. Although more pre-clinical studies in aged rodents are being done to address this shift in demographics, comprehensive transcriptomic ...
Corey Fehlberg, Danny John, Brian Kang, James S. Choi, Susana Cerqueira, Alexis Brake, Jae K. Lee   +6 more
doaj   +1 more source

Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster [PDF]

, 1976
A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi.
Benzer, Seymour, Siddiqi, Obaid
core   +1 more source