On Paralysis of the Extensors [PDF]
Journal of the Royal Society of Medicinen ...
openaire +2 more sources
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia
Journal of NeuroinflammationTraumatic brain injury (TBI) initiates a cascade of cellular and molecular events that promote acute and long-term patterns of neuronal, glial, vascular, and synaptic vulnerability leading to lasting neurological deficits. These complex responses lead to
Nadine A. Kerr +6 more
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Hospital discharges-based search of acute flaccid paralysis cases 2007-2016 in Italy and comparison with the National Surveillance System for monitoring the risk of polio reintroduction [PDF]
, 2019 Background Acute flaccid paralysis (AFP) surveillance has been adopted globally as a key strategy for monitoring the progress of the polio eradication initiative. Hereby, to evaluate the completeness of the ascertainment of AFP cases in Italy, a hospital-
Stefanelli P. +8 more
core +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
Relationships between sleep paralysis and sleep quality: current insights [PDF]
, 2018 Dan Denis1,2 1Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2Department of Psychiatry, Harvard Medical School, Boston, MA, USA Abstract: Sleep paralysis is the unusual experience of waking up in the night without the ...
Denis D
core
Late Diaphragmatic Paralysis After Atrial Fibrillation Cryoablation [PDF]
Atrial fibrillation (AF), a common cardiac arrhythmia, is often managed with catheter ablation, specifically cryoablation, to electrically isolate pulmonary veins by tissue freezing.
Özge Çakmak Karaaslan, Ümit Güray
core +1 more source
Neurobiology of Disease, 2020 Remyelination failure is a crucial component of disease progression in the autoimmune demyelinating disease Multiple Sclerosis (MS). The regenerative capacity of oligodendrocyte progenitor cells (OPCs) to replace myelinating oligodendrocytes is likely ...
Stephanie L. Yahn +5 more
doaj +1 more source