Results 61 to 70 of about 9,235 (218)

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

PERIODIC PARALYSIS.

JAMA: The Journal of the American Medical Association, 1905
n ...
openaire   +1 more source

Comparative Profiling of Mouse and Human Microglial Small Extracellular Vesicles Reveals Conserved Core Functions with Distinct miRNA Signatures

Cells
Microglia-derived small extracellular vesicles (MGEVs) are key mediators of neuroimmune communication, yet their cross-species comparability and translational relevance remain poorly defined.
Amir-Hossein Bayat, Damien D. Pearse, Praveen Kumar Singh, Mousumi Ghosh   +3 more
doaj   +1 more source

Physiotherapy in the treatment of infantile paralysis

South African Journal of Physiotherapy, 1949
No abstract available.
E. Eeg
doaj   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

PARALYSIS OF THE BLADDER [PDF]

The Journal of Nervous and Mental Disease, 1881
n ...
openaire   +2 more sources

Sustained Analgesic Peptide Secretion and Cell Labeling Using a Novel Genetic Modification

Cell Transplantation, 2008
Cell-based therapy for neuropathic pain could provide analgesics to local pain modulatory regions in a sustained, renewable fashion. In order to provide enhanced analgesic efficacy, transplantable cells may be engineered to produce complementary or ...
Shyam Gajavelli Ph.D., Daniel A. Castellanos, Orion Furmanski, Paul C. Schiller, Jacqueline Sagen   +4 more
doaj   +1 more source

Activation of Brainstem Neurons During Mesencephalic Locomotor Region-Evoked Locomotion in the Cat

Frontiers in Systems Neuroscience, 2019
The distribution of locomotor-activated neurons in the brainstem of the cat was studied by c-Fos immunohistochemistry in combination with antibody-based cellular phenotyping following electrical stimulation of the mesencephalic locomotor region (MLR ...
Ioan Opris, Xiaohong Dai, Dawn M. G. Johnson, Francisco J. Sanchez, Luz M. Villamil, Songtao Xie, Cecelia R. Lee-Hauser, Stephano Chang, Larry M. Jordan, Brian R. Noga   +9 more
doaj   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Feasibility Study on Inflammasome Proteins as Biomarkers in the Cerebrospinal Fluid of Pediatric Patients with Hydrocephalus Due to Intraventricular Hemorrhage

Biomolecules
Pediatric hydrocephalus results from the overproduction, obstruction, or inability to resorb cerebrospinal fluid (CSF), which may lead to ventricular enlargement. Hydrocephalus may be secondary to other pathologies, including intraventricular hemorrhage (
MaryLourdes Andreu, Alexandra Castellanos, Robert W. Keane, Juan Pablo de Rivero Vaccari, Jennifer C. Muñoz Pareja, Helen M. Bramlett, W. Dalton Dietrich, Nadine A. Kerr, Heather J. McCrea   +8 more
doaj   +1 more source