Parameter-efficient fine-tuning on large protein language models improves signal peptide prediction. [PDF]
Zeng S, Wang D, Jiang L, Xu D.
europepmc +1 more source
Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels
This study establishes a materials‐based design framework for polymer hydrogels in tissue clearing, linking physicochemical properties to performance in tissue processing, labeling, and imaging. By analyzing rheology, swelling, porosity, antibody diffusion, mechanical performance, and thermochemical stability across platforms, this work provides a ...
Sangjae Kim +8 more
wiley +1 more source
Augmented prediction of vertebral collapse after osteoporotic vertebral compression fractures through parameter-efficient fine-tuning of biomedical foundation models. [PDF]
Kim S +7 more
europepmc +1 more source
Alumina growth narrows surface pores and seals non‐selective defects, enhancing selectivity while preserving the nanoporous graphene architecture. Additionally, the deposition enables gradient‐controlled structural modification, with intergrown alumina acting as a physical cross‐linker that stabilizes the laminar structure.
Junhyeok Kang +8 more
wiley +1 more source
Deciphering Small Molecule Diffusion Parameters Across Light Responsive Polymersome Membranes
Light‐responsive polymersomes bearing donor–acceptor Stenhouse adducts (DASAs) enable programmable control over small‐molecule transport across synthetic membranes. By systematically varying DASA density, an optimal functionalization regime is identified that maximizes light‐gated permeability.
Farzina Matubbar +7 more
wiley +1 more source
An efficient strategy for fine-tuning large language models. [PDF]
Marsh B +4 more
europepmc +1 more source
Polymorph engineering in ErMnO3 enables low‐voltage, forming‐free threshold switching with tunable negative differential resistance. Conducting orthorhombic regions embedded in an insulating hexagonal matrix provide controlled Joule‐heating‐enhanced Poole–Frenkel transport. The hexagonal phase prevents excessive heating and breakdown.
Rong Wu +8 more
wiley +1 more source
A progressive fine-tuning framework with dynamic parameter selection for low-resource peptide-GPCR interaction prediction. [PDF]
Liu M, Xu J, Liu J.
europepmc +1 more source
Liquid‐phase transmission electron microscopy enables direct observation of nucleation and growth processes in solution. This review is dedicated to the remembrance of Helmut Cölfen and highlights recent studies on complex materials—oxides, biominerals, organic–inorganic crystals—which were central to his research activity. It summarizes key milestones,
Charles Sidhoum +5 more
wiley +1 more source
Large Language Model Adaptation Strategies in Speech-Based Cognitive Screening: Systematic Evaluation. [PDF]
Taherinezhad F +8 more
europepmc +1 more source

