Results 101 to 110 of about 7,189,567 (273)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
, 2013 The parameters of temporal models, such as dynamic Bayesian networks, may be modelled in a Bayesian context as static or atemporal variables that influence transition probabilities at every time step.
Erol, Yusuf +3 more
core
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
RESEARCH OF BEHAVIOR OF TWO FIRMS BY MEANS OF VOLTERRA MODEL OF INTERACTION OF COMMUNITIES
Вестник Северо-Кавказского федерального университета, 2022 Coordinates of a steady steady state of model interaction of two firms are found in economy by comparison with two-specific Volterra model with any coefficients.
A. S. Adamchuk +2 more
doaj
Length–weight relationship and condition factor for 7 loliginid squid species in Mexican waters
Ciencias Marinas, 2019 The length–weight relationship and the condition factor are key parameters in stock assessment. Despite the fisheries potential loliginid squids have in Mexico, the group is scarcely known and no formal management has been implemented.
Jasmín Granados-Amores +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
RESEARCH OF CHANGES OF STRUCTURE OF MODEL OF THE COMPETITION OF THREE COMMUNITIES
Вестник Северо-Кавказского федерального университета, 2022 Interaction of three communities is considered during comparison of model of the competition of three firms in economy and three-specific genetic model of a reproduction of DNA. Coexistence conditions are investigated.
Stanislav Raufovich Amirokov +1 more
doaj