Results 101 to 110 of about 7,252,040 (293)

SUSY parameter determination

open access: yes, 2005
The impact of the LHC, SLHC and the ILC on the precision of the determination of supersymmetric parameters is investigated. In particular, in the point SPS1a the measurements performed at the ILC will improve by an order of magnitude the precision ...
Lafaye, R., Plehn, T., Zerwas, D.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Length–weight relationship and condition factor for 7 loliginid squid species in Mexican waters

open access: yesCiencias Marinas, 2019
The length–weight relationship and the condition factor are key parameters in stock assessment. Despite the fisheries potential loliginid squids have in Mexico, the group is scarcely known and no formal management has been implemented.
Jasmín Granados-Amores   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

RESEARCH OF CHANGES OF STRUCTURE OF MODEL OF THE COMPETITION OF THREE COMMUNITIES

open access: yesВестник Северо-Кавказского федерального университета, 2022
Interaction of three communities is considered during comparison of model of the competition of three firms in economy and three-specific genetic model of a reproduction of DNA. Coexistence conditions are investigated.
Stanislav Raufovich Amirokov   +1 more
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

APPLICATION OF PHYSICAL AND TECHNICAL METHODS FOR IDENTIFYING WIRE RESISTORS’ FAILURES CAUSES

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки, 2020
Background. The object of the study is the failure of wire resistors caused by various types of defects in parts, components, and materials used in the production of resistive sensors.
A. Ju. Dorosinskij
doaj   +1 more source

Two-parameter Sturm-Liouville problems [PDF]

open access: yes, 2012
This paper deals with the computation of the eigenvalues of two-parameter Sturm- Liouville (SL) problems using the Regularized Sampling Method, a method which has been effective in computing the eigenvalues of broad classes of SL problems (Singular, Non ...
Boucherif, A., Chanane, B.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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