Results 51 to 60 of about 1,809,581 (249)
, 1993 This note is a brief survey and a discussion of recent ideas and open problems in the understanding of an important aspect of Type Theory: how terms may depend on types. This problem is at the core of the distinction between “ad hoc” and proper polymorphism and inspired the large amount of work on “parametricity”.
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
, 2017 Change is an inherent feature of all aspects of language, and syntax is no exception. While the synchronic study of syntax allows us to make discoveries about the nature of syntactic structure, the study of historical syntax offers even greater possibilities.
Ledgeway, Adam, Roberts, Ian
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Direct parameter identification of distributed parameter systems [PDF]
International Journal of Systems Science, 2000 A new direct approach to identifying the parameters of distributed parameter systems from noise-corrupted data is introduced. The model of the system which takes the form of a set of linear or nonlinear partial differential equations is assumed known with the exception of a set of constant parameters.
Daniel Coca, Stephen A. Billings
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Accurate calibration of stereo cameras for machine vision
Journal of Computer Science and Technology, 2004 Camera calibration is an important task for machine vision, whose goal is to obtain the internal and external parameters of each camera. With these parameters, the 3D positions of a scene point, which is identified and matched in two stereo images, can ...
Liangfu Li, Zuren Feng, Yuanjing Feng
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Transport, 2018 Due to the good mechanical performances and design flexibility of Long Glass Fiber Reinforced Polypropyl-ene (LGFRP) composite, it has been increasingly used in the automotive components, in which the LGFRP components are likely to sustain different ...
Shuyong Duan +5 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source