Results 71 to 80 of about 1,809,581 (249)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
RESEARCH OF BEHAVIOR OF TWO FIRMS BY MEANS OF VOLTERRA MODEL OF INTERACTION OF COMMUNITIES
Вестник Северо-Кавказского федерального университета, 2022 Coordinates of a steady steady state of model interaction of two firms are found in economy by comparison with two-specific Volterra model with any coefficients.
A. S. Adamchuk +2 more
doaj
Nonlinear calculation of earth pressures considering displacement effect
Yantu gongcheng xuebao, 2019 There is much difference between the calculated results of ultimate earth pressure theory and the experimental ones. To solve this problem, based on the Rankine's earth pressure theory and the two-parameter method, an earth pressure method considering ...
WANG Zheng-zhen 1, 2, GONG Wei-ming 1, 2, DAI Guo-liang 1, 2, LIU Xiao-guang 3, ZHAO Xin-xin 3, GUO Hui 3
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
RESEARCH OF CHANGES OF STRUCTURE OF MODEL OF THE COMPETITION OF THREE COMMUNITIES
Вестник Северо-Кавказского федерального университета, 2022 Interaction of three communities is considered during comparison of model of the competition of three firms in economy and three-specific genetic model of a reproduction of DNA. Coexistence conditions are investigated.
Stanislav Raufovich Amirokov +1 more
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
CoRRThe educability model is a computational model that has been recently proposed to describe the cognitive capability that makes humans unique among existing biological species on Earth in being able to create advanced civilizations. Educability is defined as a capability for acquiring and applying knowledge.
openaire +2 more sources
Influence of structural parameters on characteristics of lithium battery cathode [PDF]
Электрохимическая энергетикаThe influence of the structural parameters of lithium battery cathodes on their characteristics has been studied. To explain the results obtained, a macrokinetic model of the electrode was applied, and mathematical simulation of the electrode discharge ...
Beshkarev, Mikhail A. +3 more
doaj +1 more source