Results 51 to 60 of about 230,053 (267)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Constraints to cosmological parameters through cluster evolution [PDF]

open access: yesProceedings of the International Astronomical Union, 2004
3 pages; 3 encapsulated figures.
Del Popolo, A., Ercan, N.
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

On Collaboration in Distributed Parameter Estimation With Resource Constraints

open access: yesIEEE Transactions on Network and Service Management
Effective resource allocation in sensor networks, IoT systems, and distributed computing is essential for applications such as environmental monitoring, surveillance, and smart infrastructure. Sensors or agents must optimize their resource allocation to maximize the accuracy of parameter estimation.
Yu-Zhen Janice Chen   +2 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Mono‐Model Parameter Joint Inversion by Gramian Constraints: EM Methods Examples

open access: yesEarth and Space Science, 2019
Joint inversions of coincident geophysical data are usually constrained to produce more reliable subsurface models. Structural, petrophysical, model parameter correlation, empirical, and transforms are some of the published constraints.
J. N. Ogunbo
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Constraints on Lorentz violation parameter through electric dipole moments

open access: yesEuropean Physical Journal C: Particles and Fields
The electric dipole moments of leptons (l-EDMs) could arise from the electrodynamics part of standard model extension (SME). In this work, we investigate the cross section of electron-positron collision in the Lorentz violation (LV) background via the l ...
Sarah Aghababaei
doaj   +1 more source

Parameter constraints of grazing response functions. Implications for phytoplankton bloom initiation

open access: yesScientia Marina, 2016
Phytoplankton blooms are events of production and accumulation of phytoplankton biomass that influence ecosystem dynamics and may also have effects on socio-economic activities.
Jordi Solé   +3 more
doaj   +1 more source

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