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ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
The Potential of Horizontal Wells for Aquifer Storage and Recovery in Saline Aquifers. [PDF]
Kreipl S, Bakker M, van Breukelen BM.
europepmc +1 more source
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Parameter extraction by holographic filtering
Applied Optics, 1982Holographic matched filter pattern recognition has been plagued by too much sensitivity to such parameters as rotation and scale. We show here how to use that sensitivity to make rapid accurate estimations of those parameters. For the particular case studied, we made signal-magnitude independent measurements of four rotation angles from -15 to +15 ...
J L, Horner, H J, Caulfield
openaire +2 more sources
Impact of parameter extraction methodology on variances of extracted parameter values
Solid-State Electronics, 2010Abstract Two general classes of strategies for extraction of compact model electrical and temperature scaling parameters are identified and compared in the present paper. Applying these to extract parameters of the p–n junction depletion capacitance, we show that the reproducibility of estimated parameter values can strongly depend on the extraction ...
Vladimir Milovanović +1 more
openaire +1 more source
Methodology for extracting thermoelectric module parameters
Proceedings of the 21st IEEE Instrumentation and Measurement Technology Conference (IEEE Cat. No.04CH37510), 2004The fundamental temperature-dependent parameters of a thermoelectric (TE) module: coefficient, electrical resistance, thermal conductance, and figure-of-merit are necessary, among other factors, for the conception of models for this type of devices. In this work we present a methodology for calculating these parameters from observable variables, which ...
Daniel Mitrani +5 more
openaire +1 more source

