Results 31 to 40 of about 36,337,967 (229)
In the process of complex engineering designs or optimizations, a large number of physical experiments or numerical simulations are required to evaluate certain performance qualities before a satisfactory result can be obtained.
Yong Shao +5 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Naturally occurring gas hydrates are regarded as an important future source of energy and considerable efforts are currently being invested to develop methods for an economically viable recovery of this resource.
Carlos Giraldo +3 more
doaj +1 more source
A self-organizing state-space-model approach for parameter estimation in Hodgkin-Huxley-type models of single neurons [PDF]
Traditional approaches to the problem of parameter estimation in biophysical models of neurons and neural networks usually adopt a global search algorithm (for example, an evolutionary algorithm), often in combination with a local search method (such as ...
Aston, John A. D. +16 more
core +2 more sources
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
The temperature distribution inside a radiant heater for cooking purposes has not yet been fully investigated. A numerical methodology was developed to analyze the heat transfer inside a radiant heater.
Yun Ji Kang +6 more
doaj +1 more source
Parameter Redundancy with Applications in Statistical Ecology [PDF]
This thesis is concerned with parameter redundancy in statistical ecology models. If it is not possible to estimate all the parameters, a model is termed parameter redundant.
Hubbard, Ben Arthur
core
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
Comparing parameter choice methods for regularization of ill-posed problems [PDF]
In the literature on regularization, many different parameter choice methods have been proposed in both deterministic and stochastic settings. However, based on the available information, it is not always easy to know how well a particular method will ...
Bauer, F., Lukas, M.A.
core
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source

