Results 51 to 60 of about 36,337,967 (229)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Numerical Modelling and Parametric Study of Steel-Concrete Composite Slim-Floor Flexural Beam Using Dowel Shear Connectors

open access: yesInfrastructures
The use of steel-concrete composite slim-floor beams with dowel shear connectors is uncommon, and the design rules provided in Eurocode 4 for composite construction are not directly applicable to the slim-floor composite beam.
Xinxin Xu, Xianghe Dai, Dennis Lam
doaj   +1 more source

Parameter Identifiability and Redundancy: Theoretical Considerations [PDF]

open access: yes, 2010
Background - Models for complex biological systems may involve a large number of parameters. It may well be that some of these parameters cannot be derived from observed data via regression techniques.
Wolfgang F Heidenreich   +10 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Model Reduction of LPV Control with Bounded Parameter Variation Rates [PDF]

open access: yes, 2006
This paper proposes a reduced-order controller of linear parameter varying systems. The parameters are available for measurement while their ranges and rates of variation are assumed to be bounded.
Riyanto, T. Bambang, Widowati, Widowati
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A Parameter Study of Localization

open access: yesShock and Vibration, 1996
Extensive work has been done on the vibration characteristics of perfectly periodic structures. Disorder in the periodic pattern has been found to lead to localization in one-dimensional periodic structures.
Sandor Stephen Mester, Haym Benaroya
doaj   +1 more source

Casting innovative aerospace design case studies in the parameter analysis framework to uncover the design process of experts

open access: yesDesign Science, 2016
Traditional aerospace design methods offer quick and efficient ways to generate new designs, but such that often resemble previous ones. For truly innovative design, however, a different approach is needed.
Ehud Kroll, Ido Farbman
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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