Results 41 to 50 of about 591,132 (266)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Typology and Design of Parametric Cat-in-a-Box and Cat-in-a-Grid Triggers for Tropical Cyclone Risk Transfer

open access: yesMathematics
The insurance industry has used parametric solutions to transfer catastrophe risks since the 1990s. Instead of relying on a lengthy process to assess a claim, these products pay the insured a pre-agreed amount if the physical characteristics of the event
Guillermo Franco   +6 more
doaj   +1 more source

Parametric and Nonparametric Population Pharmacokinetic Models to Assess Probability of Target Attainment of Imipenem Concentrations in Critically Ill Patients

open access: yesPharmaceutics, 2021
Population pharmacokinetic modeling and simulation (M&S) are used to improve antibiotic dosing. Little is known about the differences in parametric and nonparametric M&S.
Femke de Velde   +10 more
doaj   +1 more source

Parametric Subtyping for Structural Parametric Polymorphism

open access: yesProceedings of the ACM on Programming Languages
We study the interaction of structural subtyping with parametric polymorphism and recursively defined type constructors. Although structural subtyping is undecidable in this setting, we describe a notion of parametricity for type constructors and then exploit it to define parametric subtyping , a conceptually simple,
Henry DeYoung   +3 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Consistency and Stability in Feature Selection for High-Dimensional Microarray Survival Data in Diffuse Large B-Cell Lymphoma Cancer

open access: yesData
High-dimensional survival data, such as microarray datasets, present significant challenges in variable selection and model performance due to their complexity and dimensionality.
Kazeem A. Dauda, Rasheed K. Lamidi
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Tips for Statistical Tools for Research Methods in Exercise and Sport Sciences

open access: yesPhysical Education Theory and Methodology, 2023
Study purpose. The increasing amount of research in Exercise and Sport Sciences emphasized the use of increasingly heuristic statistical tools appropriate to the aim in terms of qualitative, quantitative, and qualitative-quantitative data.
Sara Aliberti   +2 more
doaj   +1 more source

Parametric and non-parametric minima

open access: yesManuscripta Mathematica, 1984
Let \(u\in BV(G)\) be a local minimum for the non-parametric area functional \(\int \sqrt{1+| Du|^ 2}\).
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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