Results 61 to 70 of about 591,132 (266)

Bibliometric Study of the Efficiency of Public Expenditure on Education

open access: yesRevista CEA, 2020
This bibliometric study analyzes the literature on the efficiency of public education expenditure using two types of bibliometric indicators: quantity (number of publications) and quality (impact by year, author, and journal).
Juliana Arias-Ciro
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A unified and comprehensible view of parametric and kernel methods for genomic prediction with application to rice

open access: yesFrontiers in Genetics, 2016
One objective of this study was to provide readers with a clear and unified understanding ofparametric statistical and kernel methods, used for genomic prediction, and to compare some ofthese in the context of rice breeding for quantitative traits ...
Laval Jacquin   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Selection of Superior Potato (Solanum tuberosum L.) by Combined Stability Analysis for Future Breeding Strategies

open access: yesAgriculture
Potato is one of the main agricultural commodities and has high economic value. Yield is a trait that becomes a benchmark for user (industry and farmers) in selecting and developing varieties.
Maulana Haris   +10 more
doaj   +1 more source

Estimator Statistics from Simulation-Free Dirichlet Block-Bootstrap Resampling

open access: yesStats
Since the initiation of two variants of the bootstrap method by Efron and Rubin in the late 1970s, a variety of advancements has emerged in the literature. The subsampling of blocks enabled the estimation of the actual variance of the sample mean.
Tillmann Rosenow
doaj   +1 more source

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