Results 81 to 90 of about 617,160 (267)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Recent advances in terahertz parametric generation and detection using lithium niobate

open access: yesApplied Physics Express
We have advanced the research and development of injection-seeded terahertz (THz) parametric generation and detection as a widely tunable, and coherent THz wave source and receiver, and have applied this technology to non-destructive spectroscopy and ...
Kodo Kawase, Sota Mine, Kosuke Murate
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Practical Model for the Calculation of Lateral Electromagnetic Loads in Tokamaks at Asymmetric Vertical Displacement Events (AVDEs)

open access: yesPlasma
This paper describes a new practical numerical model for the calculation of lateral electromagnetic (EM) loads in tokamaks during asymmetric vertical displacement events (AVDEs). The model combines key features of two recently reported trial models while
Sergey Sadakov   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Application of first-order sensitivity analysis to stabilisation of unstable continuous multi-degree-of-freedom parametric periodic systems

open access: yesStudia Geotechnica et Mechanica
From a practical point of view, the most important feature of a parametric periodic system is the instability phenomenon. Unlike in systems with constant coefficients, in which only points of instability exist, in parametric systems, whole areas of ...
Wójcicki Zbigniew
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Sketches and parametrization

open access: yesTheoretical Computer Science, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dominique Duval, Pascale Sénéchaud
openaire   +1 more source

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