Results 61 to 70 of about 65,965 (261)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

On the Computation of Degenerate Hopf Bifurcations for n-Dimensional Multiparameter Vector Fields

International Journal of Mathematics and Mathematical Sciences, 2016
The restriction of an n-dimensional nonlinear parametric system on the center manifold is treated via a new proper symbolic form and analytical expressions of the involved quantities are obtained as functions of the parameters by lengthy algebraic ...
Michail P. Markakis, Panagiotis S. Douris   +1 more
doaj   +1 more source

Comprehensive calculation and safety assessment of parametric roll of very large container ship

Zhongguo Jianchuan Yanjiu, 2017
As the significant variation of GM in waves for very large container ships, strict demands are raised for this ship type in the evaluation and safety assessment of parametric roll.
MA Chengyuan, MA Ning, WANG Tinghao, GU Xiechong   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Modeling parametric solids based on arbitrary framework and non-uniform linear interpolation

Омский научный вестник
This article describes a method for constructing a parametric solid based on a framework consisting of a set of curved hexagonal portions whose opposite boundaries of non-rectangular quadrilateral faces have different parametric lengths.
T. V. Ayusheyev, Ts. Ts. Tsydypov, K. A. Filippova   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Stability approach for periodic delay Mathieu equation by the He- multiple-scales method

Alexandria Engineering Journal, 2018
In the present work, the version of homotopy perturbation included time-scales is applied to the governing equation of time-periodic delay Mathieu equation. Periodical structure for the amplitude of the zero-order perturbation is constructed.
Yusry O. El-Dib
doaj   +1 more source

Opacity calculations of plasmas by using parametric potentials

Laser and Particle Beams, 1996
A numerical model for opacity calculations by using a family of analytical potentials for each configuration in the plasma is presented. The obtained numerical opacity results with this model are compared with those obtained by using a self-consistent potential model.
P. Martel, J.M. Gil, R. Rodríguez, L. Doreste, P. Martel, J.M. Gil, E. Mínguez   +6 more
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Diferencias de los ingresos laborales entre los puestos de trabajo asalariado y los puestos de trabajo autogenerados en el Perú, 2007-2011

Desarrollo y Sociedad, 2013
The main objective of the work is to test the existence of differences in earnings between salaried jobs and self-generated jobs in the labor markets of Peru. To this purpose it uses data from household surveys from 2007 to 2011.
José S. Rodríguez
doaj   +1 more source