Results 101 to 110 of about 1,042,408 (297)

Riccati-parameter solutions of nonlinear second-order ODEs

open access: yes, 2008
It has been proven by Rosu and Cornejo-Perez in 2005 that for some nonlinear second-order ODEs it is a very simple task to find one particular solution once the nonlinear equation is factorized with the use of two first-order differential operators. Here,
Berkovich L M   +6 more
core   +2 more sources

Parametric change point detection with random occurrence of the change point

open access: yes, 2022
We are concerned with the problem of detecting a single change point in the model parameters of time series data generated from an exponential family. In contrast to the existing literature, we allow that the true location of the change point is itself random, possibly depending on the data. Under the alternative, we study the case when the size of the
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Program Linier Parametrik

open access: yesDesimal, 2019
This study aims to discuss a linear program problem where its constants can change, If a constant for a linear program problem is changed, then we don't need to count from the beginning again.
Adolf T Simatupang
doaj   +1 more source

Estimation and Decomposition of TFP Growth in the Presence of Inefficiency and Production Risk [PDF]

open access: yes
This paper addresses estimation and decomposition of total factor productivity (TFP) change. Usually TFP change is decomposed into technical change and scale effects. If inefficiency exists, it also contributes to productivity change.
Subal Kumbhakar
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Segmentation of Three-dimensional Images with Parametric Active Surfaces and Topology Changes [PDF]

open access: yes, 2015
In this paper, we introduce a novel parametric method for segmentation of three-dimensional images. We consider a piecewise constant version of the Mumford-Shah and the Chan-Vese functionals and perform a region-based segmentation of 3D image data.
Benninghoff, Heike, Garcke, Harald
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice

open access: yesData in Brief, 2017
Here we provide data describing the time-course of blood-glucose and fluid-intake profiles of diabetic hemizygous human-amylin (hA) transgenic mice orally treated with rutin, and matched control mice treated with water.
Jacqueline F. Aitken   +12 more
doaj   +1 more source

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