Results 71 to 80 of about 167,710 (314)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Does money matter in the IS curve? The case of the UK [PDF]
Narrow and broad money measures (including Divisia aggregates) have been found to have explanatory power for UK output in backward-looking specifications of the IS curve. In this paper, we explore whether or not real balances enter into a forward-looking
Stracca, Livio, Jones, Barry E.
core
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
PARAMETRIC ROSE AS A SUBJECT OF MATHEMATICS, PROGRAMMING, AESTHETICS.
Ìнформаційні технології в освіті, 2017 By using MATLAB we demonstrate a variety of parametric curves of the family "Parametric Rose" (Rhodonea), characterized by four factors. The article is intended to encourage students to study the parametric curves.
Yevgeny Gayev, Daria Malinina
doaj
Use of nonparametric regression methods for developing a local stem form model
Journal of Forest Science, 2014 A local mean stem curve of spruce was represented using regression splines. Abilities of smoothing spline and P-spline to model the mean stem curve were evaluated using data of 85 carefully measured stems of Norway spruce. For both techniques the optimal
K. Kuželka, R. Marušák
doaj +1 more source
Comparing parametric and semi-parametric approaches for bayesian cost-effectiveness analyses in health economics [PDF]
We consider the problem of assessing new and existing technologies for their cost-effectiveness in the case where data on both costs and effects are available from a clinical trial, and we address it by means of the cost-effectiveness acceptability curve.
Andrea Tancredi, Caterina Conigliani
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Accurate and Efficient Algorithm for the Closest Point on a Parametric Curve
, 2008 This paper presents an accurate and efficient method for computation of the closest point on parametric curves. This problem is firstly formulated in terms of solution of a polynomial equation expressed in Bernstein basis, and then based on subdivision ...
Li L(李论) +3 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source