Results 81 to 90 of about 431,056 (283)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Non Parametric Confidence Intervals for Receiver Operating Characteristic Curves [PDF]

open access: yes
We study methods for constructing confidence intervals, and confidence bands, for estimators of receiver operating characteristics. Particular emphasis is placed on the way in which smoothing should be implemented, when estimating either the ...
Peter G. Hall, Rob J. Hyndman, Yanan Fan
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Urban Motion Planning Framework Based on N-Bézier Curves Considering Comfort and Safety

open access: yesJournal of Advanced Transportation, 2018
In last decades, great technology advances have been done related to the automotive sector, especially in Advanced Driver Assistance Systems (ADAS) developed to improve mobility in terms of comfort and safety during driving process; hence, automated ...
Ray Lattarulo   +5 more
doaj   +1 more source

Explicit Formulas for Non-Geodesic Biharmonic Curves of the Heisenberg Group

open access: yes, 2003
We consider the biharmonicity condition for maps between Riemannian manifolds (see [BK]), and study the non-geodesic biharmonic curves in the Heisenberg group H_3.
Caddeo, R., Oniciuc, C., Piu, P.
core   +1 more source

PARAMETRIZING ELLIPTIC CURVES BY MODULAR UNITS [PDF]

open access: yesJournal of the Australian Mathematical Society, 2015
It is well known that every elliptic curve over the rationals admits a parametrization by means of modular functions. In this short note, we show that only finitely many elliptic curves over $\mathbf{Q}$ can be parametrized by modular units. This answers a question raised by W. Zudilin in a recent work on Mahler measures.
openaire   +4 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Examination of the Circle Spline Routine [PDF]

open access: yes, 1985
The Circle Spline routine is currently being used for generating both two and three dimensional spline curves. It was developed for use in ESCHER, a mesh generating routine written to provide a computationally simple and efficient method for building ...
Dolin, R. M., Jaeger, D. L.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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