Results 51 to 60 of about 354,890 (263)
Multi-Objective Optimizing Curvilinear Steel Bar Structures of Hyperbolic Paraboloid Canopy Roofs
Buildings, 2020 The paper concerns shaping curvilinear steel bar structures that are hyperbolic paraboloid canopy roofs by means of parametric design software Rhinoceros/Grasshopper and Karamba 3D.
Jolanta Dzwierzynska
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Computer-Aided Modeling In Parametric Landscape Design
Düzce University Faculty of Forestry Journal of ForestryIn this study, the possibilities of using parametric design in landscape architecture are examined through the design process and design elements. Three different computer-aided design programs, which play an important role in parametric design, were ...
Fazilet Muhammed Çolak +1 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Ambiente ConstruídoResumo Comumente, a concepção de sistema estrutural e seu projeto preliminar deveriam estar nos estágios iniciais do desenvolvimento do projeto da forma arquitetônica.
Felipe Tavares da Silva
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Application of Freeform Surface to the Parametric Design of Plate Sheet Structure
Chemical Engineering Transactions, 2018 This paper constructs a small-scale, lightweight structure with complex freeform surfaces via parametric design. First, the method of freeform surface modelling and parametric design were introduced, and combined into the parametric design aided freeform
Wei Zhang +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source