Results 51 to 60 of about 9,961,576 (291)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Geometric Thinking in Parametric Design Creativity: A Theory-Building Literature Analysis [PDF]
Journal of Design ThinkingThis study develops a conceptual framework that elucidates the role of geometric thinking in fostering creativity within parametric design processes. While geometric thinking has long been recognized as central to spatial cognition in architecture and ...
Hosein Naseri +2 more
doaj +1 more source
Buildings, 2021 Temporary pavilions play an important role as experimental fields for architects, designers, and engineers, in addition to providing exhibition spaces.
Jerzy F. Łątka, Michał Święciak
doaj +1 more source
Scalability: parametric strategies from exoskeletons to the city [PDF]
, 2010 This research will explore and provide an initial study into the diversity of contemporary computational design methodologies emerging in the field of architecture.
B. Coorey, Coorey, BP
core
Introducing Experience Goals into Packaging Design [PDF]
, 2016 Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi +3 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Journal of DaylightingParametric design is one of the thriving contemporary architectural treatments that not only has an influence on the design of building envelopes but is capable of affecting the users physically and psychologically.
Yasmine Mahmoud Saad Abdelhamid +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source