Results 91 to 100 of about 3,069,996 (290)
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
We investigate the spontaneous parametric down-conversion (SPDC) process in biaxial nonlinear crystal BiB3O6 (BIBO) with a broadband pump. Under the type I and type II phase-matching conditions, we numerically calculate the influencing factors on SPDC ...
Zhao, Wei +4 more
core +1 more source
Anti-Zeno effect in parametric down-conversion [PDF]
© 1998 The American Physical Society. We wish to thank Professor G. García-Alcaine for a careful reading of the manuscript.Two examples are presented where the observation of the emission in parametric down-conversion leads to its enhancement instead of ...
Luis Aina, Alfredo +1 more
core +1 more source
Quantum nonlinear interferometers (QNIs) can measure the infrared physical quantities of a sample by detecting visible photons. A QNI with Michelson geometry based on the spontaneous parametric down-conversion in a second-order nonlinear crystal is ...
Liu-Long Wang (11424799) +9 more
core +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Photon correlations in type-I optical parametric down-conversion
We develop a quantum theory for photon-pair correlations in type-I spontaneous parametric down-conversion, including crystal dispersion. We obtain different amplitudes for the correlations of degenerate (identical frequencies) and non-degenerate ...
Sarkar, S; id_orcid +2 more
core +3 more sources
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Absolute measurement of detector quantum efficiency using optical parametric down-conversion has been extensively studied for the case of a continuous wave pump.
Lu SL,Chinese Acad Sci,Inst Semicond,Natl Lab Superlattices & Microstruct,POB 912,Beijing 100083,Peoples R China. +5 more
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