Results 81 to 90 of about 118,549 (265)

Rapid parametric density estimation

open access: yesCoRR, 2017
Parametric density estimation, for example as Gaussian distribution, is the base of the field of statistics. Machine learning requires inexpensive estimation of much more complex densities, and the basic approach is relatively costly maximum likelihood estimation (MLE).
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Efficiency of Average Treatment Effect Estimation When the True Propensity Is Parametric

open access: yesEconometrics, 2019
It is well known that efficient estimation of average treatment effects can be obtained by the method of inverse propensity score weighting, using the estimated propensity score, even when the true one is known.
Kyoo il Kim
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Enhancing Fault Ride-Through Capacity of DFIG-Based WPs by Adaptive Backstepping Command Using Parametric Estimation in Non-Linear Forward Power Controller Design

open access: yesIEEE Access
The principal issue associated with wind parks (WPs) based on doubly-fed induction generators (DFIGs) is their vulnerability to network faults. This paper presents a novel nonlinear forward power controller design with an adaptive backstepping command ...
Azeddine Loulijat   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

PARAMETRIC SYNTHESIS OF MODELS FOR MULTICRITERIAL ESTIMATION OF TECHNOLOGICAL SYSTEMS

open access: yesСучасний стан наукових досліджень та технологій в промисловості, 2017
The subject matter of the article is the problem of multicriteria estimation of the properties of technological systems (TS) in the process of their structural-parametric optimization. The goal of the study is to increase the efficiency of procedures for
Vladimir Beskorovainyi
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Numerical modelling and robust parametric estimation of surfaces useful for representation of tooth flanks

open access: yesComputer Assisted Methods in Engineering and Science, 2023
This paper concerns modelling of surfaces resulting from measurements or from digital simulation of surfaces e.g., tooth flanks, based on the theory of gearing, with intentionally introduced modification usually defined in discrete form.
Andrzej Kawalec
doaj  

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