Results 131 to 140 of about 881,566 (302)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Vibration suppression and energy transfer by parametric excitation in drive systems

, 2012
Drive systems may experience torsional vibrations due to various kinds of excitation mechanisms. In many engineering systems, however, such vibrations may have a negative impact on the performance and must be avoided or reduced to an acceptable level ...
Pumhössel, Thomas, Ecker, Horst
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Damping by Parametric Stiffness Excitation: Resonance and Anti-Resonance

, 2009
The goal of this work is to develop deeper insight into the method of damping vibrations by means of parametric excitation in mechanical systems - employing the concept of the so-called parametric anti-resonance.
Dohnal, Fadi
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Optimal Control of a Harmonic Oscillator with Parametric Excitation

Mathematics
This paper addresses the time-optimal control problem for a harmonic oscillator characterized by a time-dependent frequency. The primary objective is to determine the minimal time required to transition the system from an initial state, defined by a ...
Dmitrii Kamzolkin, Victor Ilyutko, Vladimir Ternovski   +2 more
doaj   +1 more source

Parametric Excitation of a Ferrimagnetic Sphere Resonator

Advanced Quantum Technologies
ABSTRACT The response of a ferrimagnetic sphere resonator to an externally applied parametric excitation is experimentally studied. Measurement results are compared with predictions derived from a theoretical model, which is based on the hypothesis that disentanglement spontaneously occurs in quantum systems.
openaire   +2 more sources

Parametric Excitation in the Self-excited Vibration System with Dry Friction : 1st Report, Parametric Resonance

Bulletin of JSME, 1983
An application of solutions of linear Mathieu equation by a new method gives approximate solutions in a parametrically excited self-excitation system with dry friction. Steady solutions and the stability in the regions of parametric resonance of first and second orders are determined.
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source