Results 111 to 120 of about 881,566 (302)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The dynamics of a vibromachine with parametric excitation

open access: yes, 2001
The dynamic of a vibration machine with piecewise linear elastic ties under parametric harmonic excitation is ...
Belovodskiy, Valeriy Nikolayevich   +2 more
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

1965] “Parametric excitation of a nonlinear system

open access: yes, 2020
A study has been made on the parametric excitation of a nonlinear system with hardening springs. In the parametric excitation of linear systems, the only subharmonic predicted is a subharmonic of order 1/2.
T K Caughey, W K Tso
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Nonlinear parametric excitation of an evolutionary dynamical system

open access: yes, 2011
Nonlinear parametric excitation refers to the nonlinear analysis of a system of ordinary differential equations with periodic coefficients. In contrast to linear parametric excitation, which offers determinations of the stability of equilibria ...
Richard H Rand   +2 more
core   +1 more source

Multiparticle simulation of adiabatic excitation of longitudinal parametric resonances

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2001
In order to further understand phenomena observed during studies of adiabatic excitation of longitudinal bunch shape oscillations [M. Bai et al., Phys. Rev. ST Accel. Beams 3, 064001 (2000)], we have developed a simulation using a one-turn map.
K. A. Brown   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Study of additional parametric excitation on reduction of forced resonance vibrations

open access: yes, 2014
This contribution deals with active reduction of unacceptable vibrations by means of parametric excitation fulfilling certain conditions. It is studied on the case of 2DOF system with additional parametric excitation under harmonic force excitation.
Šulc, Petr
core  

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