Results 41 to 50 of about 702,666 (251)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Dual-Parameter Extensions of the Cat-in-a-Grid Approach for Tropical Cyclone Parametric Insurance

open access: yesRisks
Parametric insurance products for tropical cyclone risk transfer typically rely on maximum wind speed (MWS) as the only trigger parameter. While interpretable and widely used, it nevertheless leaves a substantial portion of loss variance unexplained ...
Wenwen Chen   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Bivariate box plots based on quantile regression curves

open access: yesDependence Modeling, 2020
In this paper, we propose a procedure to build bivariate box plots (BBP). We first obtain the theoretical BBP for a random vector (X, Y). They are based on the univariate box plot of X and the conditional quantile curves of Y|X. They can be computed from
Navarro Jorge
doaj   +1 more source

Hellinger Information Matrix and Hellinger Priors

open access: yesEntropy, 2023
Hellinger information as a local characteristic of parametric distribution families was first introduced in 2011. It is related to the much older concept of the Hellinger distance between two points in a parametric set.
Arkady Shemyakin
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Optimum filter synthesis with DPLMS method for energy reconstruction

open access: yesEuropean Physical Journal C: Particles and Fields, 2023
Optimum filters are granted increasing recognition as valuable tools for parametric estimation in many scientific and technical fields. The DPLMS method, introduced some twenty years ago, is especially effective among the synthesis algorithms since it ...
V. D’Andrea   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Cascading parametric decay coupling between whistler and ion acoustic waves: Darwin particle-in-cell simulations

open access: yesFrontiers in Astronomy and Space Sciences, 2022
We present the results of numerical studies of the whistler wave parametric decay instability in the system with the suppressed Landau damping of ion acoustic waves (IAWs) based on the self-consistent Darwin particle-in-cell (PIC) model.
Scott Karbashewski   +3 more
doaj   +1 more source

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