Results 91 to 100 of about 379,530 (310)

Comparing parametric and semi-parametric approaches for bayesian cost-effectiveness analyses in health economics [PDF]

open access: yes
We consider the problem of assessing new and existing technologies for their cost-effectiveness in the case where data on both costs and effects are available from a clinical trial, and we address it by means of the cost-effectiveness acceptability curve.
Andrea Tancredi, Caterina Conigliani
core  

Parametric-Based Models for Artistic Representations

open access: yes
  Driven by the popular adoption of AI for artistic purposes, this research examines its  technical and ethical implications, and presents new approaches for parametric algo rithms that generate different type of artistic representations, based on ...
Manuel Rodriguez Ladron de Guevara (17872518)
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A simulation study of a parametric mixture model of three different distributions to analyze heterogeneous survival data

open access: yes, 2013
In this paper a simulation study of a parametric mixture model of three different distributions is considered to model heterogeneous survival data.Some properties of the proposed parametric mixture of Exponential, Gamma and Weibull are investigated.The ...
Mohammed, Yusuf Abbakar   +2 more
core   +1 more source

Comparison of Parametric Rate Models for Gap Times Between Recurrent Events

open access: yesMathematics
Over the past two decades, substantial efforts have been made to develop survival models for gap times between recurrent events. An emerging approach involves considering rate models derived from a non-homogeneous Poisson process, thus allowing the ...
Ivo Sousa-Ferreira   +2 more
doaj   +1 more source

GEO Communication Satellite Engineering Design Code [PDF]

open access: yesفصلنامه علوم و فناوری فضایی, 2018
The significance and the wide use of geostationary communication satellites and the long hours of work in the process of their conceptual design was the main motivation to develop a software based on the statistical design to reduce the time spent on the
Zeynab Aghajani   +2 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Bayesian parametric models for survival prediction in medical applications. [PDF]

open access: yesBMC Med Res Methodol, 2023
Paolucci I   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A non-parametric investigation of risk premia

open access: yes
This paper investigates features of credit risk using non-parametric techniques, studying determinants of risk premia using a non-parametric term-structure model of the corporate spread. The model, which measures the extra return of defaultable corporate
Peroni, Chiara
core   +2 more sources

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