Results 71 to 80 of about 379,530 (310)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A parametric macromodelling technique [PDF]
, 2009 With the ever growing complexity of high-frequency systems in the electronic industry, formation of reduced-order models or compact macromodels of these systems is paramount.
Georgi G. Grahovski +3 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Semi-Parametric Hedonic Models, and Empirical Comparison [PDF]
Hedonic models have been widely used in the literature for valuation of non- market goods such as air quality. While the inclusion of air quality variables in hedonic models is common in applied work, there is not theoretical basis for defining the ...
Nancy Lozano-Gracia
core
Can We Improve Parametric Cyclonic Wind Fields Using Recent Satellite Remote Sensing Data?
Remote Sensing, 2018 Parametric cyclonic wind fields are widely used worldwide for insurance risk underwriting, coastal planning, and storm surge forecasts. They support high-stakes financial, development and emergency decisions.
Yann Krien +11 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Improving Parametric Mortgage Prepayment Models with Non-parametric Kernel Regression [PDF]
Developing a good prepayment model is a central task in the valuation of mortgages and mortgage-backed securities but conventional parametric models often have bad out-of-sample predictive ability.
Michael Marschoun +2 more
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Bayesian Joint Modeling of Longitudinal and Survival Time Measurement of Hypertension Patients
Risk Management and Healthcare Policy, 2020 Markos Abiso Erango College of Natural Science, Department of Statistics, Arba Minch University, Arba Minch, EthiopiaCorrespondence: Markos Abiso Erango Email markos.erango73@gmail.comBackground: High blood pressure is a health risk for all populations ...
Erango MA
doaj
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source