Results 131 to 140 of about 379,530 (310)
A new approach to bootstrap inference in functional coefficient models [PDF]
We introduce a new, factor based bootstrap approach which is robust under heteroskedastic error terms for inference in functional coefficient models. Modeling the functional coefficient parametrically, the bootstrap approximation of an F statistic is ...
Herwartz, Helmut, Xu, Fang
core
Bayesian parametric bootstrap for models with intractable likelihoods
, 2019 In this paper it is demonstrated how the Bayesian parametric bootstrap can be adapted to models with intractable likelihoods. The approach is most appealing when the computationally efficient semi-automatic approximate Bayesian computation (ABC) summary ...
Christopher C. Drovandi +8 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Parametric Macromodels of Drivers for SSN Simulations
, 2003 This paper addresses the modeling of output and power supply ports of digital drivers for accurate and efficient SSN simulations. The proposed macromodels are defined by parametric relations, whose parameters are estimated from measured or simulated port
Chen, Z. +4 more
core +1 more source
Concept of Complex-Valued Parametric Pulse Models
EURASIP Journal on Advances in Signal Processing, 2006 In pulse-based radar systems, the knowledge of certain parameters of the received radar pulse is of great importance. We introduce a complex-valued parametric pulse model by extending a real-valued pulse signal into the complex plane. A modulation angle
Stelzer Andreas +2 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Algebraic theory of identification in parametric models
The article presents the problem of identification in parametric models from an algebraic point of view. We argue that it is not just another perspective but the proper one.
Kociecki, Andrzej
core
Environmental Efficiency Measurement with Translog Distance Functions: A Parametric Approach [PDF]
We use a flexible parametric hyperbolic distance function to estimate environmental efficiency when some outputs are undesirable. Cuesta and Zofio (J. Prod.
Zofío, José Luis +2 more
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source