Results 71 to 80 of about 93,288 (302)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Analysis of Parametric and Subharmonic Excitation in Push-Pull Driven Disk Resonator Gyroscopes

open access: yesMicromachines, 2021
For micro-electromechanical system (MEMS) resonators, once the devices are fabricated and packaged, their intrinsic quality factors (Q) will be fixed and cannot be changed, which seriously limits the further improvement of the resonator’s performance. In
Kai Wu   +7 more
doaj   +1 more source

Parametric Resonance in Immersed Elastic Boundaries

open access: yesSIAM Journal on Applied Mathematics, 2004
Summary: We investigate the stability of a fluid-structure interaction problem in which a flexible elastic membrane immersed in a fluid is excited via periodic variations in the elastic stiffness parameter. This model can be viewed as a prototype for active biological tissues such as the basilar membrane in the inner ear, or heart muscle fibers ...
Ricardo Cortez   +3 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Dynamics of a dual-mass resonant vibration screen in a first approximation

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2018
The decision on creation of a new energy-efficient vibration screen using combination parametrical resonance is presented. The decision makes it possible to expand functional and operational opportunities of vibration machines.
N. N. Dentsov, A. V. Koshelev
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The oscillator's model with broken symmetry

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2015
The equations of the oscillator motion are considered. The exact solutions are given in the form of exponents with an additional parameter that characterizes the asymmetry of the oscillations.
Dmitry B Volov
doaj   +1 more source

The Smart Detection of Ship Severe Roll Motions and Decision-Making for Evasive Actions

open access: yesJournal of Marine Science and Engineering, 2020
This paper presents a numerical model for the smart detection of synchronous and parametric roll resonance of a ship. The model implements manoeuvring equations superimposed onto ship dynamics in waves.
Maria Acanfora, Flavio Balsamo
doaj   +1 more source

Parametric resonance in the early Universe—a fitting analysis [PDF]

open access: yes, 2016
Particle production via parametric resonance in the early Universe, is a non-perturbative, non-linear and out-of-equilibrium phenomenon. Although it is a well studied topic, whenever a new scenario exhibits parametric resonance, a full re-analysis is ...
Daniel G. Figueroa, F. Torrenti
semanticscholar   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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