Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Rolling mill roll design [PDF]
In this thesis, some previously published experimental and theoretical studies of hot rolling are reviewed. A thorough understanding of the available roll design methods, and conditions of their application is extremely important in order to achieve the ...
Jing, Limei
core
Cilj ovog rada bio je opisati parametarsko ljuljanje broda i uvjete koje je potrebno ispuniti da bi došlo do te pojave. Čimbenici koji utječu na parametarsko ljuljanje broda mogu se podijeliti na čimbenike ovisne o brodu ili o uvjetima okoliša ...
Štimac, Ana
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Containership route optimization considering ship synchronous rolling and parametric rolling
Maritime transportation is the backbone of global trade, but containerships face severe safety risks of container loss due to synchronous rolling and parametric rolling under complex sea conditions.
Jinfeng Zhang +5 more
doaj +1 more source
A Prototype of Ship Routing Decision Support System for an Operational Oceanographic Service [PDF]
A prototype for an operational ship routing Decision Support System using time-dependent meteo-oceanographic fields is presented. The control variable is ship course, which is modified using a directional resolution of less than 27 degrees.
Gianandrea Mannarini +3 more
doaj +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Development of Downtime Cost Calculator for Offloading Operations Influenced by Parametric Rolling [PDF]
The stability of FPSO or offloading shuttle tanker may be affected in wave conditions which excite parametric rolling. The offloading operations are thereby ceased and eventually leads to loss in production which affects the revenue of global production,
Ng Cheng Yee +4 more
core +2 more sources
Dynamic Characteristics of Cylinder Push in Bearing Cylindrical Roller Detection System
Aiming at the problem that there is no dynamic analysis of the roller pushing process during the measurement of cylindrical roller dimensions,the model of the cylindrical roller push process is established based on the working principle of the ...
CHEN Xiao-jian +4 more
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source

