Results 91 to 100 of about 32,943,257 (245)
BuildingsReinforced concrete (RC) beams strengthened with carbon-fabric-reinforced cementitious matrix (CFRCM) systems have shown potential for restoring flexural performance, yet their effectiveness under different corrosion levels remains insufficiently ...
Chaoqun Zeng +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
BuildingsInternal insulation plasters enable historic building renovation without altering the external appearance of the wall. However, the use of internal insulation must be verified case-by-case through dynamic hygrothermal simulation, and the influence of ...
Eleonora Leonardi +5 more
doaj +1 more source
Non-parametric production analysis under alternative price conditions. [PDF]
The literature on non-parametric production analysis has formulated tests for profit maximizing behavior that do not require a parametric specification of technology.
Kuosmanen, T, Cherchye, Laurens, Post, T
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Efficiency Analysis of German Electricity Distribution Utilities : Non-Parametric and Parametric Tests [PDF]
This paper applies parametric and non-parametric and parametric tests to assess the efficiency of electricity distribution companies in Germany. We address traditional issues in electricity sector benchmarking, such as the role of scale effects and ...
von Hirschhausen, Christian R. +1 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Thermal simulation of a flat-plate solar collector based on heat transfer coefficients
Frontiers in Thermal EngineeringRenewable energy plays a crucial role in mitigating environmental impact and reducing dependence on fossil fuels. Solar thermal energy offers a clean and sustainable alternative.
Ángel Alfonso García López +6 more
doaj +1 more source
A Parametric Approach to 3D Massing and Density Modelling
, 2012 This paper addresses the current void between social agendas, environmental criteria and design methodology in urban planning through the implementation of new computational systems.
M. Luther, G. Pitts
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source