Results 101 to 110 of about 150,907 (313)

Nonlinear poro thermal vibration and parametric excitation in a magneto-elastic embedded nanobeam using homotopy perturbation technique

Curved and Layered Structures
The primary focus of this study is to analyze the nonlinear vibration patterns and parametric excitation of embedded Euler–Bernoulli nanobeams subjected to thermo-magneto-mechanical loads.
Anitha Lakshmanan, Vadivukarasi Loganathan, Selvamani Rajendran, Dimitri Rossana, Tornabene Francesco   +4 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Simultaneous multi-parametric acquisition and reconstruction techniques in cardiac magnetic resonance imaging: Basic concepts and status of clinical development [PDF]

, 2022
Katerina Eyre, Katherine Lindsay, Saad Razzaq, Michael Chetrit, Matthias G. Friedrich   +4 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A Novel Intelligent Technique of Invariant Statistical Embedding and Averaging via Pivotal Quantities for Optimization or Improvement of Statistical Decision Rules under Parametric Uncertainty

, 2020
Nicholas A. Nechval, Gundars Bērziņš, Konstantin N. Nechval   +2 more
openalex   +1 more source

A Robust Parametric Technique for Multipath Channel Estimation in the Uplink of a DS-CDMA System [PDF]

, 2006
Vassilis Kekatos, Athanasios A. Rontogiannis, Kostas Berberidis   +2 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Propensity score method: a non-parametric technique to reduce model dependence. [PDF]

Ann Transl Med, 2017
Zhang Z.
europepmc   +1 more source

Parametric Optimisation of Friction-Stir-Spot-Welded Al 6061-T6 Incorporated with Silicon Carbide Using a Hybrid WASPAS–Taguchi Technique [PDF]

, 2022
Neeru Chaudhary, Sarbjit Singh, Mohinder Pal Garg, Harish Kumar Garg, Shubham Sharma, Changhe Li, Sayed M. Eldin, Samah Elsayed Elkhatib   +7 more
openalex   +1 more source