Results 121 to 130 of about 668,152 (312)
Using parametric set constraints for locating errors in CLP programs
, 2002 This paper introduces a framework of parametric descriptive directional types for constraint logic programming (CLP). It proposes a method for locating type errors in CLP programs and presents a prototype debugging tool.
Drabent, W. +2 more
core +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Extended parametric representation of compressor fans and turbines. Volume 1: CMGEN user's manual [PDF]
A modeling technique for fans, boosters, and compressors has been developed which will enable the user to obtain consistent and rapid off-design performance from design point input.
Converse, G. L., Giffin, R. G.
core +1 more source
Testing Ultrafast Two-Photon Spectral Amplitudes via Optical Fibres
, 2010 We test two-dimensional TPSA of biphoton light emitted via ultrafast spontaneous parametric down-conversion (SPDC) using the effect of group-velocity dispersion in optical fibres.
Brida, G. +5 more
core +1 more source
Cole's Parametric Search Technique Made Practical
, 2013 Parametric search has been widely used in geometric algorithms. Cole's improvement provides a way of saving a logarithmic factor in the running time over what is achievable using the standard method. Unfortunately, this improvement comes at the expense of making an already complicated algorithm even more complex; hence, this technique has been mostly ...
Goodrich, Michael T., Pszona, Paweł
openaire +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Instrumental Variables Estimation of Heteroskedastic Linear Models Using All Lags of Instruments [PDF]
We propose and evaluate a technique for instrumental variables estimation of linear models with conditional heteroskedasticity. The technique uses approximating parametric models for the projection of right hand side variables onto the instrument space ...
Ka-fu Wong +2 more
core
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Interactive solution-adaptive grid generation [PDF]
TURBO-AD is an interactive solution-adaptive grid generation program under development. The program combines an interactive algebraic grid generation technique and a solution-adaptive grid generation technique into a single interactive solution-adaptive ...
Choo, Yung K., Henderson, Todd L.
core +1 more source