Results 101 to 110 of about 668,152 (312)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Coherent Atom Interactions Mediated by Dark-State Polaritons [PDF]
, 2001 We suggest a technique to induce effective, controllable interactions between atoms that is based on Raman scattering into an optical mode propagating with a slow group velocity. The resulting excitation corresponds to the creation of spin-flipped atomic
A. André +35 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A phase-locked frequency divide-by-3 optical parametric oscillator
, 2000 Accurate phase-locked 3:1 division of an optical frequency was achieved, by using a continuous-wave (cw) doubly resonant optical parametric oscillator.
Clairon, A. +4 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Jixie chuandong, 2008 A method to exploit worm gear and worm parametric system with UG/OPEN API was introduced.Under the VC environment,worm gear tooth contact strength and tooth root bending strength were checked,and a database system about worm gear and worm material and ...
周卿, 赵韩, 吴振华, 张建国
doaj
On the kinematic deconvolution of the local neighbourhood luminosity function [PDF]
, 2001 A method for inverting the statistical star counts equation, including proper motions, is presented; in order to break the degeneracy in that equation it uses the supplementary constraints required by dynamical consistency.
A. Siebert +28 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Spatial Resolution of Attenuation Imaging
Archives of Acoustics, 2014 The attenuating properties of biological tissue are of great importance in ultrasonic examination even though its anatomical variability limits diagnostics effectiveness.
Ziemowit KLIMONDA +2 more
doaj