Results 101 to 110 of about 917,742 (295)

Hypothesis testing for two population means: parametric or non-parametric test?

open access: yes, 2019
The parametric Welch $t$-test and the non-parametric Wilcoxon-Mann-Whitney test are the most commonly used two independent sample means tests. More recent testing approaches include the non-parametric, empirical likelihood and exponential empirical ...
Alenazi, Abdulaziz   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Assessing the performance of parametric and non‐parametric tests for trend detection in partial duration time series

open access: yesJournal of Flood Risk Management
The detection of nonstationarities in partial duration time series (PDS) depends on several factors, including the length of the time series, the selected statistical test, and the heaviness of the tail of the distribution.
Renato Amorim, Gabriele Villarini
doaj   +1 more source

An Alternative Sense of Asymptotic Efficiency [PDF]

open access: yes
The paper studies the asymptotic efficiency and robustness of hypothesis tests when models of interest are defined in terms of a weak convergence property.
Mueller, Ulrich
core   +1 more source

A Panel Test of Purchasing Power Parity Under the Null of Stationarity [PDF]

open access: yes, 2001
Purchasing Power Parity (PPP) is tested using a sample of real exchange rate data for twelve European countries. Acknowledging that Augmented Dickey Fuller tests have low power, we apply a Panel test that considers the null of stationarity and corrects
Hunter, J, Simpson, M
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Semi-Parametric Indirect Inference [PDF]

open access: yes
We develop in this paper a generalization of the Indirect Inference (II) to semi-parametric settings and termed Semi-parametric Indirect Inference (SII).
Eric Renault, Ramdan Dridi
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Towards a novel design method for impact on leading edges [PDF]

open access: yes, 2006
Results of a parametric study concerning low velocity impact on leading edge profiles is presented. This work is the first part of a larger program on the development of an engineering design method for impact on Glare.
Houten, M.H. van, Kaplan, H.
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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