Results 71 to 80 of about 24,151,088 (246)
Three-dimensional model of aspects of religion/spirituality.
, 2023 Three-dimensional model of aspects of religion/spirituality.
Constantin Klein (11331401) +3 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Three-dimensional fluid model considering the oil film thickness.
, 2022 Three-dimensional fluid model considering the oil film thickness.
Hongqiang Chai (13170571) +4 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Parametric relaxation in whispering gallery mode exciton-polariton condensates [PDF]
, 2015 This work has been supported by Leipzig School of Natural Sciences BuildMoNa (GS 185/1), the European Social Fund (ESF) within Nachwuchsforschergruppe “Multiscale functional structures,” and DFG-FOR1616 (SCHM2710/2-1,P1) “Dynamics and Interactions of ...
Sturm, C. +9 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Journal of Engineering, 2019 In this study, a three-dimensional model with multi-parameter order reduction is applied to the thermal modelling of power electronics modules with complex geometries.
Xiaojun Dong +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Synthesis of facial ageing transforms using three-dimensional morphable models [PDF]
, 2009 Supplementary material restricted permanentlyThe ability to synthesise the effects of ageing in human faces has numerous uses from aiding the search for missing people to improving recognition algorithms and aiding surgical planning.
Hunter, David W.
core +2 more sources