Results 1 to 10 of about 14,362 (191)

Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]

PLoS Pathogens, 2010
The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J Holtzman, Marco Colonna   +6 more
doaj   +5 more sources

Henipavirus in Northern Short-Tailed Shrew, Alabama, USA [PDF]

Emerging Infectious Diseases
RNA metagenomic analysis of tissues from 4 wild-caught northern short-tailed shrews in Alabama, USA, revealed a novel henipavirus (family Paramyxoviridae).
Rhys H. Parry, KayLene Y.H. Yamada, Wendy R. Hood, Yang Zhao, Jinlong Y. Lu, Andrei Seluanov, Vera Gorbunova, Naphak Modhiran, Daniel Watterson, Ariel Isaacs   +9 more
doaj   +3 more sources

Multi-Epitope-Based Peptide Vaccine Against Bovine Parainfluenza Virus Type 3: Design and Immunoinformatics Approach [PDF]

Veterinary Sciences
Bovine parainfluenza virus type 3 (BPIV3) is a significant pathogen implicated in bovine respiratory disease complex (BRDC), leading to lung tissue destruction, immunosuppression, and subsequent bacterial infections in cattle, hence incurring ...
Junbo Wang, Pu Wang, Fangyuan Tian, Qiang Liu, Meimei Hai, Zijie Guo, Yuanwen Wang, Yong Li, Yujiong Wang   +8 more
doaj   +2 more sources

Henipaviruses—A constant threat to livestock and humans

PLoS Neglected Tropical Diseases, 2022
In this review, we highlight the risk to livestock and humans from infections with henipaviruses, which belong to the virus family Paramyxoviridae. We provide a comprehensive overview of documented outbreaks of Nipah and Hendra virus infections affecting
Susann Kummer, Denise-Carina Kranz
doaj   +2 more sources

Probable Human Infection with a Newly Described Virus in the Family Paramyxoviridae [PDF]

Emerging Infectious Diseases, 1998
After an apparently new virus in the family Paramyxoviridae was isolated from pigs in August 1997, an investigation was carried out to assess its risk for humans. More than 250 persons with potential exposure to infected pigs were tested serologically. Two piggery workers with intense occupational exposure had high convalescent-phase antibody titers to
Kerry Chant, Raymond Chan, Mitchell Smith, Dominic E. Dwyer, Peter D. Kirkland   +4 more
openaire   +2 more sources

Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier

mBio, 2021
Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance.
Neeta Shrestha, Flavio Max Gall, Cyrille Mathieu, Melanie Michaela Hierweger, Melanie Brügger, Marco P. Alves, Jonathan Vesin, Damiano Banfi, David Kalbermatter, Branka Horvat, Marc Chambon, Gerardo Turcatti, Dimitrios Fotiadis, Rainer Riedl, Philippe Plattet   +14 more
doaj   +1 more source

Revealing Berberis aristata potential as an anti-viral agent to combat Paramyxoviridae infection

Journal of Environmental Biology, 2022
Aim: To study the anti-viral activity of extracts of Berberis aristata and to scrutinize the novel lead compound present in it probably to combat Paramoxyviridae infection. Methodology: The phytochemicals present in the barks of Berberis aristata were extracted and screened by GC-MS analysis.
Y.S. Shreenivasan, S. Keerthana, A. Praveena, P. Dhasarathan   +3 more
openaire   +1 more source

Superinfection is associated with short-term outcome and mortality in viral respiratory tract infections during the fall-winter seasons 2016-2018 in the Greater Paris area: the SUPERFLUOUS study

International Journal of Infectious Diseases, 2022
: Background: Following a study of predictors of superinfection in viral respiratory tract infections (VRTIs), this study analyzes the predictors of the outcome.
Benjamin Davido, Benoit Lemarie, Elyanne Gault, Marion Pepin, Karim Jaffal, Sebastien Beaune, Lotfi Dahmane, Jennifer Dumoulin, Segolene Greffe, Djillali Annane, Pierre De Truchis   +10 more
doaj   +1 more source

Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses

Immuno, 2023
Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown, Tanya Gravier, Ingo Fricke, Suhaila A. Al-Sheboul, Theodor-Nicolae Carp, Chiuan Yee Leow, Chinua Imarogbe, Javad Arabpour   +7 more
doaj   +1 more source

Viral metagenomics of pharyngeal secretions from children with acute respiratory diseases with unknown etiology revealed diverse viruses

Virus Research, 2022
Acute respiratory tract infections are a major public health problem and the leading cause of morbidity in children younger than 5 years old. This study investigated the potential reasons of unexplained acute respiratory infections in children in Xuzhou ...
Qingqing Mao, Guangming Sun, Yu Qian, Yuchen Qian, Wang Li, Xiaochun Wang, Quan Shen, Shixing Yang, Chenglin Zhou, Hao Wang, Wen Zhang   +10 more
doaj   +1 more source