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, 2020 Motility disorders represent the most common form of gastrointestinal involvement during malignancy and belong to the wide spectrum of paraneoplastic neurologic syndromes (PNSs). These conditions result from an immune-mediate injury to the enteric nervous system (ENS).
Ursini, Francesco +4 more
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International Journal of Molecular Sciences, 2020 Skin manifestations of systemic disease and malignancy are extremely polymorphous. Clinicians should be familiarized with paraneoplastic dermatoses in order to perform an early diagnosis of the underlying neoplasm.
Dario Didona +2 more
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CellFor people with a rare cancer-associated condition called paraneoplastic syndrome, sudden memory loss, loss of coordination, or other neurological symptoms are often the first sign that a tumor is growing somewhere in the body. The symptoms are caused by
Tammy L Smith, Jason D Shepherd
exaly +2 more sources
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The Journal of Dermatology, 2007
ABSTRACTParaneoplastic pemphigus (PNP) is a life‐threatening autoimmune blistering skin disease. Clinically, it is characterized by severe mucosal erosions and various cutaneous lesions associated with lymphoproliferative neoplasmas. Suprabasal acantholysis and clefts with scattered necrotic keratinocytes are the unique histopathological features.
Xuejun, Zhu, Bingxin, Zhang
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ABSTRACTParaneoplastic pemphigus (PNP) is a life‐threatening autoimmune blistering skin disease. Clinically, it is characterized by severe mucosal erosions and various cutaneous lesions associated with lymphoproliferative neoplasmas. Suprabasal acantholysis and clefts with scattered necrotic keratinocytes are the unique histopathological features.
Xuejun, Zhu, Bingxin, Zhang
openaire +4 more sources
Current Opinion in Rheumatology, 2009
It has been recognized for some time now, that compared with the normal population, patients with idiopathic inflammatory myopathies (IIM) live with an increased risk of developing malignancy. In the majority of these patients, cancer-associated myositis appears to have some paraneoplastic features. The aim of the present review is to describe new data
Dankó, Katalin +4 more
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It has been recognized for some time now, that compared with the normal population, patients with idiopathic inflammatory myopathies (IIM) live with an increased risk of developing malignancy. In the majority of these patients, cancer-associated myositis appears to have some paraneoplastic features. The aim of the present review is to describe new data
Dankó, Katalin +4 more
openaire +3 more sources
Dermatologic Clinics, 1993
Paraneoplastic pemphigus is a newly recognized disease that occurs in some patients with lymphoproliferative neoplasms and occasionally, solid tumors. Patients present with an acute illness of the mucosa and skin that shares clinical and histologic features with erythema multiforme, toxic epidermal necrolysis, and pemphigus vulgaris.
D F, Mutasim, N J, Pelc, G J, Anhalt
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Paraneoplastic pemphigus is a newly recognized disease that occurs in some patients with lymphoproliferative neoplasms and occasionally, solid tumors. Patients present with an acute illness of the mucosa and skin that shares clinical and histologic features with erythema multiforme, toxic epidermal necrolysis, and pemphigus vulgaris.
D F, Mutasim, N J, Pelc, G J, Anhalt
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Current Opinion in Neurology, 1991
Most nervous system paraneoplastic syndromes probably result from an immune attack against antigens normally expressed only in the nervous system but aberrantly expressed in a cancer. Specific antibodies in serum and cerebrospinal fluid that react with the nervous system and the cancer can be used to characterize proteins usually restricted to the ...
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Most nervous system paraneoplastic syndromes probably result from an immune attack against antigens normally expressed only in the nervous system but aberrantly expressed in a cancer. Specific antibodies in serum and cerebrospinal fluid that react with the nervous system and the cancer can be used to characterize proteins usually restricted to the ...
openaire +3 more sources
Epilepsy & Behavior, 2016
Epilepsy can be a manifestation of paraneoplastic syndromes which are the consequence of an immune reaction to neuronal elements driven by an underlying malignancy affecting other organs and tissues. The antibodies commonly found in paraneoplastic encephalitis can be divided into two main groups depending on the target antigen: 1) antibodies against ...
Anna, Serafini +6 more
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Epilepsy can be a manifestation of paraneoplastic syndromes which are the consequence of an immune reaction to neuronal elements driven by an underlying malignancy affecting other organs and tissues. The antibodies commonly found in paraneoplastic encephalitis can be divided into two main groups depending on the target antigen: 1) antibodies against ...
Anna, Serafini +6 more
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Equine Veterinary Education, 2011
Summary A paraneoplastic syndrome is a disease or symptom that is a consequence of the presence of neoplasia, but is not due to the local presence of neoplastic cells. The pathophysiology of paraneoplastic syndromes is complex. Paraneoplastic syndromes may precede the detection of an active malignancy, and thorough investigation is ...
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Summary A paraneoplastic syndrome is a disease or symptom that is a consequence of the presence of neoplasia, but is not due to the local presence of neoplastic cells. The pathophysiology of paraneoplastic syndromes is complex. Paraneoplastic syndromes may precede the detection of an active malignancy, and thorough investigation is ...
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Neurologic Clinics, 2013
Paraneoplastic causes are a rare but important diagnostic consideration when evaluating myelopathy because neurologic symptoms may herald a diagnosis of cancer. Spinal cord MRI findings of longitudinally extensive, symmetric, tract-specific T2-signal changes occasionally with gadolinium enhancement are characteristic.
Eoin P, Flanagan, B Mark, Keegan
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Paraneoplastic causes are a rare but important diagnostic consideration when evaluating myelopathy because neurologic symptoms may herald a diagnosis of cancer. Spinal cord MRI findings of longitudinally extensive, symmetric, tract-specific T2-signal changes occasionally with gadolinium enhancement are characteristic.
Eoin P, Flanagan, B Mark, Keegan
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