Results 81 to 90 of about 10,930 (229)

Claustrum Sign in Hashimoto Encephalopathy Presenting With New Onset Refractory Status Epilepticus (NORSE): First Report of a Rare Phenotype

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT The presence of the bilateral claustrum sign in new‐onset refractory status epilepticus (NORSE) should prompt consideration of Hashimoto's encephalopathy, even without thyroid dysfunction. Early recognition and corticosteroid therapy can be lifesaving, emphasizing an autoimmune‐inflammatory mechanism underlying this rare presentation.
Zahra‐Sadat Mirian, Mohammad Amin Najafi, Alireza Anjam Majoumerd, Ali Khoshnevisan, Mohammad Reza Najafi   +4 more
wiley   +1 more source

Paraneoplastic cerebellar degeneration and psychosis in uterine malignancy

Archives of Mental Health, 2017
Paraneoplastic Neurological Syndromes (PNS) are a group of rare disorders that occur in people with malignancies due to autoimmune mediated mechanisms affecting the central or peripheral nervous system.
Arul R Saravanan, Rajkumar Ramanathan, T V Asokan   +2 more
doaj  

CircRbfox1 Contributes to Colonic Hypersensitivity in Rats With Diabetes by Altering HuC Subcellular Localization to Regulate RBFOX1 Expression

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
circRbfox1 mediates diabetic colonic hypersensitivity by binding the RNA‐binding protein HuC, facilitating its nuclear translocation in T13‐L2 DRGs. This enhances transcription of the parent gene Rbfox1, culminating in increased expression of the L‐type calcium channel Cav1.3.
Shiyu Zhang, Ji Hu, Chendong Ni, Yilian Zhang, Jiahao Chen, Yajing Liu, Shufen Hu, Fuchao Zhang, Guang‐Yin Xu, Hong‐Hong Zhang   +9 more
wiley   +1 more source

What is the significance of onconeural antibodies for psychiatric symptomatology? A systematic review

BMC Psychiatry, 2017
Background Patients with intracellular onconeural antibodies may present with neuro-psychiatric syndromes. We aimed to evaluate the evidence for an association between well-characterized onconeural antibodies and psychiatric symptoms in patients with and
Sverre Georg Sæther, Morten Schou, Daniel Kondziella   +2 more
doaj   +1 more source

Application of a synthetic human proteome to autoantigen discovery through PhIP-Seq [PDF]

, 2014
In this study, we improve on current autoantigen discovery approaches by creating a synthetic representation of the complete human proteome, the T7 “peptidome” phage display library (T7-Pep), and use it to profile the autoantibody repertoires of ...
Church, George M., Ciccia, Alberto, Elledge, Stephen J., Gakidis, M. Angelica Martinez, Kesari, Santosh, Larman, H. Benjamin, Laserson, Uri, LeProust, Emily M., Li, Mamie Z., Solimini, Nicole L., Zhao, Zhenming   +10 more
core   +1 more source

Post‐COVID‐19 Area Postrema Syndrome With SARS‐CoV‐2 in CSF: A Dual‐Case Report and Review of the Literature

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
This dual‐case report describes two patients with post‐COVID‐19 area postrema syndrome whose outcomes were dictated by their AQP4‐IgG serostatus, despite both having SARS‐CoV‐2 detected in their CSF. The stark contrast between the seronegative patient's recovery and the seropositive patient's fatal relapse highlights antibody testing as an urgent and ...
Wan Zhu, Jing Qian, Min Peng, Yan Li, Jinghan Hu   +4 more
wiley   +1 more source

Therapeutic decision making in autoimmune and inflammatory disorders of the central nervous system in children. [PDF]

, 2016
Autoimmune and inflammatory disorders of the central nervous system can result in significant morbidity and mortality. Through the recognition of syndromes using diagnostic biomarkers, the clinician is now able to use immune suppressive therapies to ...
Dale, Rc, Lim, M., Nosadini, M
core   +3 more sources

Case Report: Anti-Yo antibody mediated paraneoplastic cerebellar degeneration in a patient with squamous cell lung carcinoma

Frontiers in Immunology
Paraneoplastic cerebellar degeneration (PCD) is a heterogeneous group of neurologic syndromes associated with primary tumors. It is postulated that the immune system targets a tumor antigen that is also expressed endogenously in the nervous system.
Chen-Hao Yang, Yan Xu, Si-Yuan Fan
doaj   +1 more source

Prevalence and clinical characteristics of serum neuronal cell surface antibodies in first-episode psychosis: a case-control study [PDF]

, 2017
$\textbf{Background}$ Psychosis is a common presenting feature in antibody-mediated encephalitis, for which prompt recognition and treatment usually leads to remission.
Lennox, BR, Palmer-Cooper, EC, Pollak, T, Hainsworth, J, Marks, J, Jacobson, L, Lang, B, Fox, H, Ferry, B, Scoriels, Linda, Crowley, H, Jones, Peter, Harrison, PJ, Vincent, A   +13 more
core   +1 more source

Cancer Neuroscience: Innovative Conception and Emerging Strategy of Therapy

MedComm, Volume 7, Issue 4, April 2026.
In this review, we summarize nerve–cancer interactions and conclude two additional interactions, “perineural invasion” and “neuro‐microbic‐oncology.” Emphasizing the important role of nerves in tumor progression. The nervous system also contributes to the development of cancer comorbidities such as cancer depression and cognitive dysfunction.
Ting Wang, Zikai Dong, Yongfei Wang, Ziyi An, Siyuan Wang, Wei‐Lin Jin   +5 more
wiley   +1 more source