Results 101 to 110 of about 163,147 (181)
Paraneoplastic Syndromes Associated With Small Cell Lung Cancer
, 2006 Small cell lung cancer (SCLC) is the most frequent cancer histology associated with paraneoplastic syndromes. These syndromes are typically caused by ectopic hormone production or immune-mediated tissue destruction caused by neural antigen expression ...
Leena Gandhi, Bruce E. Johnson
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Gephyrin Neurological Autoimmunity
Annals of Neurology, Volume 100, Issue 4, Page 781-787, October 2026.Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano +10 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by symmetric proximal muscle weakness and distinctive cutaneous manifestations. It is frequently associated with underlying malignancies, making recognition of paraneoplastic features crucial.
Manisha Chapagain +4 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT An anterior mediastinal mass in infants can present with life‐threatening complications due to airway and vascular compression. We report a six‐month‐old infant with a mature teratoma presenting as mediastinal mass syndrome, highlighting the diagnostic challenges and anesthetic risks involved.
Ghamar Taj Khanbabaee +6 more
wiley +1 more source
Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer
MedComm, Volume 7, Issue 10, October 2026.Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta +2 more
wiley +1 more source
Paraneoplastic syndromes in pancreatic cancer.
, 2018 Paraneoplastic syndromes are defined as signs and symptoms which presentdistant to the site of primary cancer or metastases. However, they are closelyassociated with the malignant disease and comprise metabolic, dystrophic, and/ordegenerative symptoms ...
Herzig, S. +3 more
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Muscle &Nerve, Volume 74, Issue 4, Page 1156-1173, October 2026.ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor +5 more
wiley +1 more source
Approach to paraneoplastic syndromes in rheumatology [PDF]
Background. Paraneoplastic syndromes (PNS) are distant effects of cancer not caused by direct tumor invasion or metastasis. In rheumatology, they often mimic autoimmune diseases, leading to diagnostic difficulties and therapeutic challenges due to ...
Nistor, Alesea, Nazeer, Nawfia
core
Paraneoplastic rheumatic syndromes
, 2006 Paraneoplastic symptoms caused by a malignancy but not directly related to tumour invasion are the result of a wide variety of tumour-derived biologic mediators, such as hormones, peptides, antibodies, cytotoxic lymphocytes, autocrine and paracrine ...
András, Csilla +4 more
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Giant Intrapulmonary Solitary Fibrous Tumour With a Possible Liver Metastasis: A Rare Case
Respirology Case Reports, Volume 14, Issue 10, October 2026.A 57‐year‐old woman presented with a giant intrapulmonary solitary fibrous tumour (SFT) that progressed from a large left lower lobe mass to extensive thoracic disease with cardiac displacement, pericardial effusion and a hepatic lesion suspicious for metastasis.
Desdiani Desdiani +3 more
wiley +1 more source