Results 81 to 90 of about 163,147 (181)

Targeted therapies in pemphigus vulgaris: Emerging horizons beyond rituximab

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Rituximab‐refractory pemphigus vulgaris is driven by B‐cell repopulation, plasma‐cell persistence, IgG4 autoantibodies and anti‐drug antibodies. This review evaluates five emerging targeted classes acting at successive steps of disease: next‐generation anti‐CD20 antibodies, DSG3‐CAAR T cells, BTK inhibitors, BAFF/APRIL inhibitors and FcRn antagonists ...
Rhea Ahuja, Dedee Murrell
wiley   +1 more source

Clinical challenges of paraneoplastic endocrine metabolic syndromes: An illustrative example

open access: yesJournal of Clinical and Translational Endocrinology Case Reports
Background/objective: Paraneoplastic endocrine metabolic syndromes are rare, but clinically significant manifestations of underlying malignancies, often complicating clinical course and impacting treatment outcomes.
Srushti Shankar   +13 more
doaj   +1 more source

Paraneoplastic Peripheral Nervous System Manifestations of Renal Cell Carcinoma: A Case Report and Review of the Literature

open access: yesCase Reports in Neurology, 2017
Neurologic symptoms secondary to a paraneoplastic syndrome may be the presenting manifestation of a previously undiagnosed cancer, and alertness to these syndromes may provide an opportunity for early detection and treatment of a cancer.
Ingrid Yang, Joanna Jaros, Danny Bega
doaj   +1 more source

Algorithms in Allergy: Treatment of Hypereosinophilic Syndromes, 2026 Update

open access: yes
Allergy, EarlyView.
Guillaume Lefèvre   +5 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini   +4 more
wiley   +1 more source

Paraneoplastic syndromes and the kidney

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2010
A paraneoplastic syndrome is defined as a group of symptoms that develop when substances released by some cancer cells disrupt the normal function of the surrounding cells and tissue. Paraneoplastic renal syndromes are diseases that indirectly compromise
de Oliveira Filgueira Pedro Henrique   +3 more
doaj  

The Role of Comorbidities in Pyoderma Among Canine and Feline Diabetic Patients

open access: yesVeterinary Dermatology, EarlyView.
Background: Pyoderma is considered a secondary complication of diabetes mellitus (DM), yet the relationship remains unclear. One study found 22% of diabetic dogs with dermatopathy had no other comorbidities, whereas cats have not been evaluated.
Virginia Wixon   +2 more
wiley   +1 more source

Paraneoplastic Syndromes in Hodgkin’s Lymphoma

open access: yes
Hodgkin’s lymphoma (HL) is a monoclonal lymphoid neoplasm that is mainly characterized by multinucleated Reed–Sternberg cells on a background of non-neoplastic inflammatory cells.
Chandravathi Loke   +3 more
core   +1 more source

Paraneoplastic syndromes in ganglioneuroblastoma: contrasting symptoms of constipation and diarrhoea [PDF]

open access: yes, 2003
A paraneoplastic syndrome is occasionally the first clinical symptom seen with tumours. We report on two children who initially presented with paraneoplastic syndromes due to ganglioneuroblastomas: the first with severe watery diarrhoea caused by a ...
Barbara Wildhaber   +9 more
core   +2 more sources

Paraneoplastic endocrine syndromes: diagnosis and management

open access: yes, 2009
peer reviewedParaneoplastic endocrine syndromes define a group of secondary signs and symptoms associated to a neoplasia, independently from the location of the primary tumor or its metastases. Paraneoplastic or ectopic endocrine syndromes usually result
Niaourou, V.   +4 more
core   +1 more source

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