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Paraneoplastic syndromes can be defined as a whole of systemic signs and symptoms related to cancer. These signs and symptoms are directly related to substances that the tumor produces or to a host’s reaction to the cancer.
Mario Scartozzi +3 more
core
Paraneoplastic Syndromes of the Central Nervous System [PDF]
In recent years a continuous stream of new information on clinical, pathological and immunological aspects of paraneoplastic neurological syndromes has been published.
Moll, J.W.B. (Wibe)
core +1 more source
Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang +6 more
wiley +1 more source
[Paraneoplastic syndromes of the central nervous system]
Paraneoplastic syndromes of central nervous system are rare neurologic syndromes caused by cancer but not secondary to metastases. The physiopathologic mechanisms underlying these syndromes are still under debate.
Scaringella P +5 more
core +1 more source
PARANEOPLASTIC SYNDROMES IN RHEUMATOLOGY [PDF]
Reumatološki paraneoplastički sindromi su rijetke i vrlo važne komplikacije i epifenomeni različitih solidnih i hematoloških malignih bolesti. Svijest o njima, razjašnjavanje patofizioloških mehanizama i prepoznavanje reumatoloških paraneoplastičnih ...
Mayer, Miroslav, Anić, Branimir
core +1 more source
Cutaneous paraneoplastic syndromes as early indicators of neoplastic diseases
Cutaneous paraneoplastic syndromes play an important role in the detection of malignant neoplasms and may represent the first clinical sign of an underlying malignancy. The skin is the second most frequently involved organ, after the endocrine system and
Julia Sawicka +5 more
doaj +1 more source
ABSTRACT Primary cutaneous gamma‐delta T‐cell lymphoma (PCGD‐TCL) is a rare cytotoxic lymphoma with key oncogenic drivers in the JAK/STAT pathway. Also primarily involving the subcutaneous adipose tissue, subcutaneous panniculitis‐like T‐cell lymphoma (SPTCL) is more frequently encountered in scenarios of autoimmune disorders.
Bennett Christie‐Nguyen +6 more
wiley +1 more source
Elevated lymphoma risk in patients with chronic pruritus and chronic prurigo
Summary Background and objectives Chronic pruritus (CP) and chronic prurigo (CPG, including prurigo nodularis) are prevalent, debilitating diseases with diverse comorbidities, including malignancies. This retrospective cohort study evaluated the prevalence and risk of lymphoma in CP and CPG patients, including key risk factors, and sex‐ and ancestry ...
Svenja Royeck +10 more
wiley +1 more source
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley +1 more source

