Results 41 to 50 of about 24,877 (234)

Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis? [PDF]

, 2013
Paraneoplastic neurological syndromes (PNSs) occur in patients with cancer and can cause clinical symptoms and signs of dysfunction of the nervous system that are not due to a local effect of the tumor or its metastases.
Jin, Tao, Ni, Fengming, Wu, Limin, Zhang, Hongliang, Zhou, Chunkui, Zhu, Jie   +5 more
core   +3 more sources

Paraneoplastic neuromuscular syndromes at the outpatient level

Медицинский вестник Юга России, 2019
Objective: to develop tactics for the differential diagnosis of paraneoplastic neuromuscular syndromes in patients at the outpatient level.Materials and methods: the study included 50 patients with classical neuromuscular paraneoplastic syndromes ...
A. E. Chertousova, I. V. Chernikova
doaj   +1 more source

Paraneoplastiline sündroom. Haigusjuhtude kirjeldus [PDF]

, 2007
Paraneoplastiline sündroom (PNS) on kasvaja indutseeritud immunoloogiline reaktsioon, mis algselt kujutab organismi kaitsemehhanismi kasvaja vastu, kuid mis tabab n-ö ekslikult närvisüsteemi rakke.
Glükmann, Meeli, Perli, Anne, Suigom , Mare, Vanakesa, Tõnu   +3 more
core   +2 more sources

No evidence for circulating HuD-specific CD8+ T cells in patients with paraneoplastic neurological syndromes and Hu antibodies [PDF]

, 2007
Aim: In paraneoplastic neurological syndromes (PNS) associated with small cell lung cancer (SCLC) and Hu antibodies (Hu-PNS), Hu antigens expressed by the tumour hypothetically trigger an immune response that also reacts with Hu antigens in the nervous ...
Janet W. de Beukelaar, Georges M. Verjans, Yvette van Norden, Johannes C. Milikan, Jaco Kraan, Herbert Hooijkaas, Kees Sintnicolaas, Jan W. Gratama, Peter A. Sillevis Smitt   +8 more
core   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Anti-PD1-/PDL1-induced chronic intestinal pseudo-obstruction: three cases treated with vedolizumab after corticosteroid failure with mixed results

Cancer Immunology, Immunotherapy
Immune checkpoint inhibitors (ICI), i.e., anti-PD1/PDL1 and anti-CTLA-4, have reshaped the prognosis of many cancers. Increased use of ICI has led to the onset of new adverse events.
Morgan Zenatri, Michael Collins, Tifanie Alberto, Antonio Farina, Sophie Collardeau-Frachon, Mélanie Saint-Jean, François Bocquet, Frederic Dumont, Jérôme Honnorat, Bastien Joubert, Judith Raimbourg   +10 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Thymic Carcinoma Associated with Cerebellar Degeneration [PDF]

, 2017
We present the case of a 57-year-old man with ataxia and clinical and radiological features of cerebellar degeneration. A computed tomography showed a mediastinal mass. The patient was diagnosed of thymic carcinoma. paraneoplastic cerebellar degeneration
García Cuartero, Irene, García del Pozo, Julián Solís, Pérez Pinar, Montserrat, Rodríguez Galdeano, Mónica   +3 more
core   +2 more sources

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer

Gynecologic Oncology Reports, 2017
Paraneoplastic syndromes are a group of rare disorders that can be triggered by an abnormal immune response to proteins from tumors of the lung, ovary, lymphatics, or breast. Paraneoplastic clinical syndromes affect
Madhumita Chatterjee, Laura C. Hurley, Michael A. Tainsky   +2 more
doaj   +1 more source