Results 21 to 30 of about 19,721 (235)

Paraneoplastic syndromes [PDF]

open access: yesCurrent Opinion in Immunology, 1997
Paraneoplastic syndromes (i.e. organ/tissue disorders associated with cancer) affecting the nervous system are thought to be the result of an autoimmune response triggered by specific cancer antigens. Several of these antigens have recently been identified and include the Hu, Yo and Ri proteins, with the Hu antigens being the best studied. Immunization
J O, Dalmau, J B, Posner
openaire   +3 more sources

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

open access: yesThe Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth   +10 more
wiley   +1 more source

Diagnosis and treatment of paraneoplastic neurological disorders [PDF]

open access: yes, 2004
In about two thirds of cases, patients with paraneoplastic neurological disorders present to the neurologist without a known tumor. Due to the ongoing immune response, this tumor tends to stay biologically relatively benign, and therefore difficult to ...
Voltz, R., Graus, F.
core   +1 more source

Paraneoplastic Cerebellar Ataxia and the Paraneoplastic Syndromes [PDF]

open access: yesBaylor University Medical Center Proceedings, 2015
Paraneoplastic cerebellar ataxia, also known as paraneoplastic cerebellar degeneration, is one of the wide array of paraneoplastic neurological syndromes in which neurological symptoms are indirectly caused by an underlying malignancy, most commonly gynecological, breast, or lung cancer or Hodgkin's lymphoma.
Sadaf, Afzal   +2 more
openaire   +2 more sources

Stiff Person Syndrome and Acetylcholine Receptor Ganglionic Neuronal Antibodies

open access: yesCase Reports in Neurology, 2020
The association between stiff person syndrome and paraneoplastic syndromes has been described, linking intracellular or extracellular antibodies. We describe the case of a 64-year-old woman with stiff person syndrome and positivity for acetylcholine ...
Jacobo Lester   +2 more
doaj   +1 more source

A rare case of concomitant Lambert–Eaton myasthenic syndrome and syndrome of inappropriate antidiuretic hormone secretion in a patient with small cell lung carcinoma

open access: yesRespiratory Medicine Case Reports, 2023
Small cell lung carcinoma (SCLC) is a neuroendocrine carcinoma with a poor prognosis and is a common cause of paraneoplastic syndromes. Paraneoplastic syndromes are characterized by neurological and endocrinological problems in patients with malignancy ...
Yasuharu Oda   +9 more
doaj   +1 more source

Paraneoplastic neurological syndromes [PDF]

open access: yesCurrent Opinion in Neurology, 2012
This review describes relevant advances in paraneoplastic neurological syndromes (PNS) with emphasis on particular syndromes and the impact of antibodies against surface antigens in their management.PNS may present with symptoms that do not raise the suspicion of a paraneoplastic origin.
Francesc, Graus, Josep, Dalmau
openaire   +2 more sources

Paraneoplastic leukemoid reaction in a patient with metastatic adenocarcinoma of the lung

open access: yesClinical Case Reports, 2020
Paraneoplastic syndromes in lung malignancies can lead to leukemoid reaction with an elevation of eosinophils, neutrophils, and monocytes. The elevation of these three lineages together due to paraneoplastic syndromes has not been described in literature
Christopher El Mouhayyar   +5 more
doaj   +1 more source

Paraneoplastic syndromes associated with tumors of the digestive system

open access: yesUniversidad Médica Pinareña, 2021
Introduction: paraneoplastic syndromes are sets of signs and symptoms affecting cancer patients, which do not depend directly on the tumor. Objective: to describe paraneoplastic syndromes associated with digestive system tumors.
Roxana Vitón-Moreno   +1 more
doaj  

Mucocutaneous Paraneoplastic Syndrome Secondary to Classical Hodgkin’s Lymphoma

open access: yesClinical Practice and Cases in Emergency Medicine, 2019
Paraneoplastic syndromes may be the only presenting manifestation of an otherwise occult malignancy. This case report highlights a patient presenting to the emergency department with an atypical, multi-system disease, ultimately leading to a diagnosis of
Jenna Jurkovic, Michael Cirone
doaj   +1 more source

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