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Paraneoplastic neurological syndromes (PNS) include any symptomatic and non-metastatic neurological manifestations associated with a neoplasm. PNS associated with antibodies against intracellular antigens, known as “high-risk” antibodies, show frequent ...
Luca Marsili +5 more
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Small-cell lung cancer-associated autoantibodies: potential applications to cancer diagnosis, early detection, and therapy [PDF]
Small-cell lung cancer (SCLC) is the most aggressive lung cancer subtype and lacks effective early detection methods and therapies. A number of rare paraneoplastic neurologic autoimmune diseases are strongly associated with SCLC.
Laird-Offringa Ite A, Kazarian Meleeneh
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Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis? [PDF]
Paraneoplastic neurological syndromes (PNSs) occur in patients with cancer and can cause clinical symptoms and signs of dysfunction of the nervous system that are not due to a local effect of the tumor or its metastases.
Hongliang Zhang +5 more
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Neuroglial markers of damage in autoimmune neurology [PDF]
The advancements in assays for the detection of neuroglial markers of damage, such as neurofilament light chain and glial fibrillary acid protein, have led to a growing interest in their investigation in neurological disorders.
Alessandro Dinoto, Sara Mariotto
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Neurological paraneoplastic syndromes are a rare subgroup of diseases commonly related to neuroendocrine tumors. However, they have been associated with uterine malignancies (sarcomas, endometrial carcinomas, and neuroendocrine cancers).
Anna Svarna +6 more
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Neurological Paraneoplastic Syndromes: the Early Diagnosis of Lung Cancer [PDF]
Paraneoplastic syndromes of the nervous system are rare disorders, strongly linked with lung cancer. This report aims to explore the challenges in the diagnosis and treatment of a patient with early-stage small cell lung cancer and neurological ...
Andreea PAROSANU +8 more
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Psychiatric manifestations of paraneoplastic syndromes
Introduction Paraneoplastic syndromes (PS) result from indirect effects of neoplasms. In 50% of the cases the symptoms precede the diagnosis and run independently.
M. Lemos, A. Lourenço, M. Ribeiro
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Diagnosis and Treatment of Paraneoplastic Neurologic Syndromes
Paraneoplastic antibody syndromes result from the anti-tumor antibody response against normal antigens ectopically expressed by tumor cells. Although this antibody response plays an important role in helping clear a nascent or established tumor, the ...
Daniel Chiu +2 more
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Paraneoplastic encephalitis associated with renal cell carcinoma [PDF]
Purpose Paraneoplastic encephalitis is autoimmune encephalitis accompanied by tumors. Renal cell carcinoma (RCC) is a kidney cancer originating from various types of renal cells and rarely has been associated with paraneoplastic neurologic manifestation.
Yoonhyuk Jang +4 more
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Paraneoplastic neurological syndromes: clinical presentations and management
We provide an overview of the varied presentations of paraneoplastic neurological syndromes. We also review the onconeural antibodies and their particular oncological and neurological associations.
Michelle F. Devine +3 more
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